Protein Alignment Ssadh and Aldh1a1

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_038949786.1
• Gene: Aldh1a1 / 24188
• RGDID: 2087
• Length: 520
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 181/489 - (37%)
• Similarity: 278/489 - (56%)
• Gaps: 31/489 - (6%)

  Fly    30 KALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYE-SKEWRSLTAKDR 93
            |..::..|.||.:.| .|.|.|||...||..|.....||..||:.||:||:: ...||::.|.:|
  Rat    41 KIFINNEWHDSVSGK-KFPVLNPATEEVICHVEEGDKADVDKAVKAARQAFQIGSPWRTMDASER 104

  Fly    94 SNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAF----------VEWFAEEARRIY 148
            ..||.|...|:|:....:|.|.....||         .:.||:          :::.|..|.:|:
  Rat   105 GRLLNKLADLMERDRLLLATIEAINGGK---------VFANAYLSDLGGSIKALKYCAGWADKIH 160

  Fly   149 GEIVPSASPNREIIVM--KQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTAL 211
            |:.:||   :.:|...  ::||||...|.|||||:.|...|.|.||:.|.||||||:|.||||||
  Rat   161 GQTIPS---DGDIFTFTRREPIGVCGQIIPWNFPLLMFIWKIGPALSCGNTVVVKPAEQTPLTAL 222

  Fly   212 AVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSA--DGIKRI 274
            .:|.|..:||.|.||:|:| .......|.......||..::|||||:||||: :.:|  ..:||:
  Rat   223 HMASLIKEAGFPPGVVNIV-PGYGPTAGAAISSHMDVDKVAFTGSTQVGKLI-KEAAGKSNLKRV 285

  Fly   275 CLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALK 339
            .|||||.:|.|||..||::.||:.|....|.:.||.||:|:|.||::||||:||.:..:|.:...
  Rat   286 TLELGGKSPCIVFADADLDIAVEFAHHGVFYHQGQCCVAASRIFVEESVYDEFVRKSVERAKKYV 350

  Fly   340 IGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQ 404
            :|:.....:..||.|::.|.:|:...:|..:.:.|.:..||....:|| .|..||:.::|....:
  Rat   351 LGNPLTQGINQGPQIDKEQHDKILDLIESGKKEGAKLECGGGRWGNKG-FFVQPTVFSNVTDEMR 414

  Fly   405 LYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIIS 469
            :..||:||||..|::|:..::.:|:||:|..|||...::::|.:...|:..|:.|:|.||..:|.
  Rat   415 IAKEEIFGPVQQIMKFKSIDDVIKRANNTTYGLAAGVFTKDLDRAITVSSALQAGVVWVNCYMIL 479

  Fly   470 AAEAPFGGVKESGVGREGSKHGIDDYVDIKYICM 503
            :|:.||||.|.||.|||..:||:.:|.::|.:.|
  Rat   480 SAQCPFGGFKMSGNGRELGEHGLYEYTELKTVAM 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	174/468 (37%)
Aldh1a1	XP_038949786.1	ALDH_F1AB_F2_RALDH1	34..514	CDD:143459	181/489 (37%)