Protein Alignment Ssadh and Aldh8a1

DIOPT Version :9

• Sequence 1: NP_001014665.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_848828.1
• Gene: Aldh8a1 / 237320
• MGIID: 2653900
• Length: 487
• Species: Mus musculus
• Alignment Length: 489
• Identity: 165/489 - (33%)
• Similarity: 269/489 - (55%)
• Gaps: 28/489 - (5%)

  Fly    30 KALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRS 94
            |.|...:::||         .:|:.|.|..||||....:.:.|::||::|:.:  |.|.:.::||
Mouse    17 KFLPCNSYIDS---------YDPSTGEVYCKVPNSGKEEIEAAVEAAREAFPA--WSSRSPQERS 70

  Fly    95 NLLKKWHKLIEQHSQEIAEIMTAESGKPINESKG-EVAYGNAFVEWFAEEARRIYGEIVPSASPN 158
            .:|.:...::||..:|:|:..:.:.||.:..::. ::........:||........|....:...
Mouse    71 LVLNRLADVLEQSLEELAQAESKDQGKTLTLARTMDIPRSVLNFRFFASSNLHHVSECTQMSHLG 135

  Fly   159 REIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIP 223
            .....::.|:|:|.||:|||.|:.::|.|...|:|||.||:.||||.|.:||....||...||:|
Mouse   136 CMHYTVRTPVGIAGLISPWNLPLYLLTWKIAPAIAAGNTVIAKPSEMTSVTAWMFCKLLDKAGVP 200

  Fly   224 KGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFD 288
            .||||:| ......:|:.....|:|..||||||....:.:.:.||...|::.|||||..|.|:|:
Mouse   201 PGVINIV-FGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFE 264

  Fly   289 SADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEAL---KIGDGQGCDVQI 350
            .|::|:.:...:.|.|.|.|:.|:..:|.|||.|:|.:|   ||:.|||.   |:|........:
Mouse   265 DANLEECIPATVRSSFANQGEICLCTSRIFVQRSIYSEF---LKRFVEATRKWKVGVPSDPSANM 326

  Fly   351 GPLINEMQFNKVSGFVEDARSKKANIILG------GQPLPDKGSLFYAPTIVTDVPPSAQLYSEE 409
            |.||::....||..:|..|:::.|.|:.|      ..||.::...|..||::||:...::..:||
Mouse   327 GALISKAHLEKVRSYVLKAQTEGARILCGEGVDQLSLPLRNQAGYFMLPTVITDIKDESRCMTEE 391

  Fly   410 VFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAP 474
            :||||..::.|..|||.:.:||..|.|||...:|:::.::.||||:|:.|:|..|..:|.....|
Mouse   392 IFGPVTCVVPFDSEEEVITRANSVRYGLAATVWSKDVGRIHRVAKKLQSGLVWTNCWLIRELNLP 456

  Fly   475 FGGVKESGVGREGSKHGIDDYVDIKYICMGNLKY 508
            |||:|.||:||||:|...|.:.:||.|   .:||
Mouse   457 FGGMKSSGIGREGAKDSYDFFTEIKTI---TIKY 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	159/463 (34%)
Aldh8a1	NP_848828.1	ALDH_F8_HMSADH	27..485	CDD:143412	160/475 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810