Protein Alignment Ssadh and ALDH3A2

DIOPT Version :9

• Sequence 1: NP_001014665.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001026976.1
• Gene: ALDH3A2 / 224
• HGNCID: 403
• Length: 508
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 120/457 - (26%)
• Similarity: 223/457 - (48%)
• Gaps: 60/457 - (13%)

  Fly    77 KQAYESKEWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFA 141
            :||:.|  .||...:.|...|:...:::::..::|...:.|:    :.:|:..|         ::
Human     9 RQAFLS--GRSRPLRFRLQQLEALRRMVQEREKDILTAIAAD----LCKSEFNV---------YS 58

  Fly   142 EEARRIYGEI------VP---SASPNR--------EIIVMKQPIGVAALITPWNFPMAMITRKAG 189
            :|...:.|||      :|   :|.|.:        |..:..||:||..:|..||:|..:..:...
Human    59 QEVITVLGEIDFMLENLPEWVTAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLI 123

  Fly   190 AALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGV---INVVTTNKAAPIGDLFCKSPDVRGI 251
            .|:|||..|::||||.:..||..:|||     :|:.:   :.:|.........:|..:..|  .|
Human   124 GAIAAGNAVIIKPSELSENTAKILAKL-----LPQYLDQDLYIVINGGVEETTELLKQRFD--HI 181

  Fly   252 SFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANR 316
            .:||:|.|||::...:|..:..:.|||||.:|..:....|::.........|:.||||||::.:.
Human   182 FYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDY 246

  Fly   317 FFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGP----LINEMQFNKVSGFVEDARSKKANII 377
            ...:.|:.::.|.::|:.|:     :..|.:::..|    :||...|.::...:|..:     |.
Human   247 ILCEASLQNQIVWKIKETVK-----EFYGENIKESPDYERIINLRHFKRILSLLEGQK-----IA 301

  Fly   378 LGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFY 442
            .||:  .|:.:.:.|||::|||.|..::..||:|||::.|:..::.:||:...|:..:.||.|.:
Human   302 FGGE--TDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVF 364

  Fly   443 SENLQQVFRVAKRLEVGMVGVNEGII--SAAEAPFGGVKESGVGREGSKHGIDDYVDIKYICMGN 505
            |.|.:.:.|:......|.|..|:.|:  :....|||||..||:|....||..|.:...:...:.:
Human   365 SHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKS 429

  Fly   506 LK 507
            ||
Human   430 LK 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	118/451 (26%)
ALDH3A2	NP_001026976.1	ALDH_F3AB	5..444	CDD:143450	120/457 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810