Protein Alignment Ssadh and ALDH9A1

DIOPT Version :9

• Sequence 1: NP_001014665.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_000687.3
• Gene: ALDH9A1 / 223
• HGNCID: 412
• Length: 518
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 167/482 - (34%)
• Similarity: 260/482 - (53%)
• Gaps: 16/482 - (3%)

  Fly    35 GAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLLKK 99
            ||.|:.::|..|.:...||.|.||.........:...|:..||.|:  |.|...:..:|..:|.:
Human    41 GARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAF--KIWSQKSGMERCRILLE 103

  Fly   100 WHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIV--PSASPNREII 162
            ..::|.:...|||.:....:||.|.|::.::......:|::|..|..:.||.:  |..|..   .
Human   104 AARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFG---Y 165

  Fly   163 VMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGVI 227
            ..::|:||...|..||:|..:.:.|:..|||.|..:|.|||..||::||.:|::..:||:|.|:.
Human   166 TRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLF 230

  Fly   228 NVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADI 292
            |||  ...|..|...|:.|||..:|||||...|..:...||.|||.:.|||||.:|.|:|...|:
Human   231 NVV--QGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDM 293

  Fly   293 EKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEM 357
            ..||.||:.:.|...||.|.:..|.|||..:.|||..::.|:.:.:||||....|.::|||||..
Human   294 NNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRP 358

  Fly   358 QFNKVSGFVEDARSKKANIILGGQ-PLPD----KGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSI 417
            ...:|.|||:.|:.:.|.::.||. .:|:    |...:..|.::|:.........||:||||:||
Human   359 HLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSI 423

  Fly   418 IRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESG 482
            :.|..|.|.:::||||..|||...::.::|:..||...|:.|...:|...:|..|.||||.|:||
Human   424 LSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSG 488

  Fly   483 VGREGSKHGIDDYVDIKYIC--MGNLK 507
            .|||..:..|:.|..:|.:|  ||:::
Human   489 FGRENGRVTIEYYSQLKTVCVEMGDVE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	160/462 (35%)
ALDH9A1	NP_000687.3	ALDH_F9_TMBADH	55..512	CDD:143409	160/463 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810