Protein Alignment Ssadh and ALDH9A1

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_000687.3
• Gene: ALDH9A1 / 223
• HGNCID: 412
• Length: 518
• Species: Homo sapiens
• Alignment Length: 482
• Identity: 167/482 - (34%)
• Similarity: 260/482 - (53%)
• Gaps: 16/482 - (3%)

  Fly    35 GAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTAKDRSNLLKK 99
            ||.|:.::|..|.:...||.|.||.........:...|:..||.|:  |.|...:..:|..:|.:
Human    41 GARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAF--KIWSQKSGMERCRILLE 103

  Fly   100 WHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIV--PSASPNREII 162
            ..::|.:...|||.:....:||.|.|::.::......:|::|..|..:.||.:  |..|..   .
Human   104 AARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLAASMAGEHIQLPGGSFG---Y 165

  Fly   163 VMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGVI 227
            ..::|:||...|..||:|..:.:.|:..|||.|..:|.|||..||::||.:|::..:||:|.|:.
Human   166 TRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLF 230

  Fly   228 NVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADI 292
            |||  ...|..|...|:.|||..:|||||...|..:...||.|||.:.|||||.:|.|:|...|:
Human   231 NVV--QGGAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAKGIKPVTLELGGKSPLIIFSDCDM 293

  Fly   293 EKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGPLINEM 357
            ..||.||:.:.|...||.|.:..|.|||..:.|||..::.|:.:.:||||....|.::|||||..
Human   294 NNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRMGPLINRP 358

  Fly   358 QFNKVSGFVEDARSKKANIILGGQ-PLPD----KGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSI 417
            ...:|.|||:.|:.:.|.::.||. .:|:    |...:..|.::|:.........||:||||:||
Human   359 HLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSI 423

  Fly   418 IRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESG 482
            :.|..|.|.:::||||..|||...::.::|:..||...|:.|...:|...:|..|.||||.|:||
Human   424 LSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSG 488

  Fly   483 VGREGSKHGIDDYVDIKYIC--MGNLK 507
            .|||..:..|:.|..:|.:|  ||:::
Human   489 FGRENGRVTIEYYSQLKTVCVEMGDVE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	160/462 (35%)
ALDH9A1	NP_000687.3	ALDH_F9_TMBADH	55..512	CDD:143409	160/463 (35%)