Protein Alignment Ssadh and ALDH3B1

DIOPT Version :9

• Sequence 1: NP_001014665.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_000685.1
• Gene: ALDH3B1 / 221
• HGNCID: 410
• Length: 468
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 118/426 - (27%)
• Similarity: 195/426 - (45%)
• Gaps: 38/426 - (8%)

  Fly    86 RSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESK-GEVAYGNAFV--------EWFA 141
            |:..|:.|:..|:...:.::::.|.:.:.:..:..|...||: .|||.....|        .|..
Human    19 RTRPAEFRAAQLQGLGRFLQENKQLLHDALAQDLHKSAFESEVSEVAISQGEVTLALRNLRAWMK 83

  Fly   142 EEARRIYGEIVPS--ASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSE 204
            :|.       ||.  |:......:.|:|.|:..:|.|||:|:.:.......|||||..||:||||
Human    84 DER-------VPKNLATQLDSAFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSE 141

  Fly   205 DTPLTALAVAKLAVDAGIPKGVIN---VVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRN 266
                .:..|.|:..:. :|:.|..   .|........|.|.....|.  |.||||..|||::...
Human   142 ----ISKNVEKILAEV-LPQYVDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTA 199

  Fly   267 SADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQL 331
            :|..:..:.|||||..|..|.|:.|.:...:.....::.|.|||||:.:.......:.::.:..|
Human   200 AAKHLTPVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLPAL 264

  Fly   332 KKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIV 396
            :..:... .||.......:|.:||:.||.::...:...|     :.:|||  .|:...:.|||::
Human   265 QSTITRF-YGDDPQSSPNLGRIINQKQFQRLRALLGCGR-----VAIGGQ--SDESDRYIAPTVL 321

  Fly   397 TDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMV 461
            .||.....:..||:|||::.|:..:..:||::..|...:.||.|.:|.:.|.|.||..:...|..
Human   322 VDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGF 386

  Fly   462 GVNEGI--ISAAEAPFGGVKESGVGREGSKHGIDDY 495
            ..|:|.  ::.|..|||||..||:||...|...|.:
Human   387 CGNDGFMHMTLASLPFGGVGASGMGRYHGKFSFDTF 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	118/426 (28%)
ALDH3B1	NP_000685.1	ALDH_F3AB	6..447	CDD:143450	118/426 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810