Protein Alignment Ssadh and ALDH1A1

DIOPT Version :9

• Sequence 1: NP_001014665.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_000680.2
• Gene: ALDH1A1 / 216
• HGNCID: 402
• Length: 501
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 174/486 - (35%)
• Similarity: 271/486 - (55%)
• Gaps: 29/486 - (5%)

  Fly    30 KALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYE-SKEWRSLTAKDR 93
            |..::..|.||.:.| .|.|.|||....:.:|......|..||:.||:||:: ...||::.|.:|
Human    22 KIFINNEWHDSVSGK-KFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASER 85

  Fly    94 SNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAF----------VEWFAEEARRIY 148
            ..||.|...|||:....:|.:.:...||         .|.||:          :.:.|..|.:|.
Human    86 GRLLYKLADLIERDRLLLATMESMNGGK---------LYSNAYLNDLAGCIKTLRYCAGWADKIQ 141

  Fly   149 GEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAV 213
            |..:| ...|.......:||||...|.|||||:.|:..|.|.||:.|.||||||:|.||||||.|
Human   142 GRTIP-IDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHV 205

  Fly   214 AKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSA--DGIKRICL 276
            |.|..:||.|.||:|:| .......|.......|:..::||||||||||: :.:|  ..:||:.|
Human   206 ASLIKEAGFPPGVVNIV-PGYGPTAGAAISSHMDIDKVAFTGSTEVGKLI-KEAAGKSNLKRVTL 268

  Fly   277 ELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIG 341
            ||||.:|.||...||::.||:.|....|.:.||.|::|:|.||::|:||:||.:..:|.:...:|
Human   269 ELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILG 333

  Fly   342 DGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLY 406
            :.....|..||.|::.|::|:...:|..:.:.|.:..||.|..:|| .|..||:.::|....::.
Human   334 NPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKG-YFVQPTVFSNVTDEMRIA 397

  Fly   407 SEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVN-EGIISA 470
            .||:||||..|::|:..::.:|:||:|..||:...:::::.:...::..|:.|.|.|| .|::|
Human   398 KEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVS- 461

  Fly   471 AEAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
            |:.||||.|.||.|||..::|..:|.::|.:
Human   462 AQCPFGGFKMSGNGRELGEYGFHEYTEVKTV 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_001014665.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	168/467 (36%)
ALDH1A1	NP_000680.2	ALDH_F1AB_F2_RALDH1	15..495	CDD:143459	174/486 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810