Protein Alignment Ssadh and Aldh5a1

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_766120.1
• Gene: Aldh5a1 / 214579
• MGIID: 2441982
• Length: 523
• Species: Mus musculus
• Alignment Length: 484
• Identity: 254/484 - (52%)
• Similarity: 355/484 - (73%)
• Gaps: 9/484 - (1%)

  Fly    26 LVQDKALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYESKEWRSLTA 90
            |::..:.|.|.|:.   |.|||.|.:||:||.:|.|.:..|.:|:.|:.||..|:.|  |:.::.
Mouse    46 LLRGDSFVGGRWLP---APATFPVYDPASGAKLGTVADCGVPEARAAVRAAYDAFNS--WKGVSV 105

  Fly    91 KDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFAEEARRIYGEIVPSA 155
            |:||.||:||:.|:.|:..::|:|:|||||||:.|::||:.|...|:|||:||||||||:|:.::
Mouse   106 KERSLLLRKWYDLMIQNKDDLAKIITAESGKPLKEAQGEILYSALFLEWFSEEARRIYGDIIYTS 170

  Fly   156 SPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDA 220
            :.::..:|:|||:||||:|||||||.||||||.||||||||||||||:||||.:|||:|:||..|
Mouse   171 AKDKRGLVLKQPVGVAAIITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPYSALALAQLANQA 235

  Fly   221 GIPKGVINVV--TTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAP 283
            |||.||.||:  :.|||..:|::.|..|.|..|||||||..||:|..::|:.:||:.:||||.||
Mouse   236 GIPAGVYNVIPCSRNKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAP 300

  Fly   284 FIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRV-EALKIGDGQGCD 347
            |||||||::::||.|||||||||.|||||.:|||.||..::|.||.:..:.: ::|::|:|....
Mouse   301 FIVFDSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGNGFEEG 365

  Fly   348 VQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFG 412
            ...||||||....||...|.||.:|.|.::.||: ....|..|:.||::::|.......:||.||
Mouse   366 TTQGPLINEKAVEKVEKQVNDAVAKGATVVTGGK-RHQSGGNFFEPTLLSNVTRDMLCITEETFG 429

  Fly   413 PVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGG 477
            |:..:|:|..|||||..||....||||||||::..|::|||::|||||||||||:||:.|.||||
Mouse   430 PLAPVIKFDKEEEAVAIANAAEVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGG 494

  Fly   478 VKESGVGREGSKHGIDDYVDIKYICMGNL 506
            ||:||:||||||:|||:|:::||:|.|.|
Mouse   495 VKQSGLGREGSKYGIDEYLEVKYVCYGGL 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	243/456 (53%)
Aldh5a1	NP_766120.1	SSADH	66..516	CDD:188167	241/452 (53%)