Protein Alignment Ssadh and Aldh4a1

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_780647.3
• Gene: Aldh4a1 / 212647
• MGIID: 2443883
• Length: 562
• Species: Mus musculus
• Alignment Length: 467
• Identity: 130/467 - (27%)
• Similarity: 218/467 - (46%)
• Gaps: 36/467 - (7%)

  Fly    51 NPANGAVIGKVPNMTVAD---AQKAIDAAKQAYESKEWRSLTAKDRSNLLKKWHKLIE--QHSQE 110
            :|.|.|  .||.....||   ..:|||||..|  .|||......||:.:..|...::.  :.::.
Mouse    82 SPFNHA--HKVAKFCYADKALLNRAIDAALAA--RKEWDLKPMADRAQVFLKAADMLSGPRRAEV 142

  Fly   111 IAEIMTAESGKPINESKGEVAYGNAFVEWF---AEEARRIYGEIVPSASPNREIIVMKQPIGVAA 172
            :|:.|..: ||.:.::  |:......:::|   |:.|..:.||...|..|:....|.:...|..|
Mouse   143 LAKTMVGQ-GKTVIQA--EIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLEGFVA 204

  Fly   173 LITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIPKGVINVVTTNKAAP 237
            .|:|:|| .|:....|||....|..|:.|||:...|.:.||.::..:||:|..:|..|..: ...
Mouse   205 AISPFNF-TAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPAD-GPT 267

  Fly   238 IGDLFCKSPDVRGISFTGSTEVGKLLFRNSADGI------KRICLELGGNAPFIVFDSADIEKAV 296
            .||....|..:.||:||||....|.|:|..|..:      .|:..|.||.....|..|||::..|
Mouse   268 FGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDSVV 332

  Fly   297 DGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGD-GQGCDVQIGPLINEMQFN 360
            .|.:.|.|...||.|.:.:|.:|..|::.:..|:|.:....:|:|| .:........:|:...|.
Mouse   333 SGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKAFA 397

  Fly   361 KVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEE- 424
            ::..::|.|||..:..||.|....:....:..|.|:....|...:..||:||||:::..:.|::
Mouse   398 RIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGPVLTVYVYPDDKY 462

  Fly   425 -EAVKKANDTRR-GLAGYFYSEN---LQQVFRVAKRLEVGMVGVNE---GIISAAEAPFGGVKES 481
             |.::..:.|.. ||.|..::::   :|:..|:. |...|...:|:   |.: ..:.||||.:.|
Mouse   463 RETLQLVDSTTSYGLTGAVFAQDKAIVQEATRML-RNAAGNFYINDKSTGSV-VGQQPFGGARAS 525

  Fly   482 GVG-REGSKHGI 492
            |.. :.|..|.|
Mouse   526 GTNDKPGGPHYI 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	130/467 (28%)
Aldh4a1	NP_780647.3	ALDH_F4-17_P5CDH	31..552	CDD:143441	130/467 (28%)