Protein Alignment Ssadh and Aldh1a2

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_033048.2
• Gene: Aldh1a2 / 19378
• MGIID: 107928
• Length: 518
• Species: Mus musculus
• Alignment Length: 481
• Identity: 161/481 - (33%)
• Similarity: 259/481 - (53%)
• Gaps: 19/481 - (3%)

  Fly    30 KALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYE-SKEWRSLTAKDR 93
            |..::..|.:|.:.: .|.|.|||.|..:.:|......|..||:.||:.|:. ...||.:.|.:|
Mouse    39 KIFINNEWQNSESGR-VFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASER 102

  Fly    94 SNLLKKWHKLIEQHSQEIAEIMTAESGKPINES-----KGEVAYGNAFVEWFAEEARRIYGEIVP 153
            ..||.|...|:|:....:|.:.:...|||..::     :|.:.....:..|    |.:|:|..:|
Mouse   103 GRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGW----ADKIHGMTIP 163

  Fly   154 SASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAV 218
             ...:.......:||||...|.|||||:.|.|.|...||..|.|||:||:|.|||:||.:..|..
Mouse   164 -VDGDYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIK 227

  Fly   219 DAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADG---IKRICLELGG 280
            :||.|.||:|:: .......|........:..|:||||||||||:  ..|.|   :||:.|||||
Mouse   228 EAGFPPGVVNIL-PGYGPTAGAAIASHIGIDKIAFTGSTEVGKLI--QEAAGRSNLKRVTLELGG 289

  Fly   281 NAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQG 345
            .:|.|:|..||::.||:.|....|.|.||.|.:.:|.||::|:|::||.:..:|.:...:|....
Mouse   290 KSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFD 354

  Fly   346 CDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEV 410
            ...:.||.|::.|:|||...::...::.|.:..||:.|..|| .|..||:.::|....::..||:
Mouse   355 PTTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGGKGLGRKG-FFIEPTVFSNVTDDMRIAKEEI 418

  Fly   411 FGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPF 475
            ||||..|:||:..:|.:::||::..||....::.::.:...|:..::.|.|.:|......|::||
Mouse   419 FGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPF 483

  Fly   476 GGVKESGVGREGSKHGIDDYVDIKYI 501
            ||.|.||.|||..:.|:.:|.::|.:
Mouse   484 GGFKMSGNGREMGEFGLREYSEVKTV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	157/462 (34%)
Aldh1a2	NP_033048.2	ALDH_F1AB_F2_RALDH1	32..512	CDD:143459	161/481 (33%)