Protein Alignment Ssadh and alh-2

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_503467.2
• Gene: alh-2 / 187001
• WormBaseID: WBGene00000108
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 498
• Identity: 174/498 - (34%)
• Similarity: 275/498 - (55%)
• Gaps: 13/498 - (2%)

  Fly    13 SSLSLCRMRGFSALVQD------KALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQK 71
            :|:..|...|....:.|      ...::..:||:.:.| |||..|||||.::.||......|...
 Worm    12 ASVQACNGSGLPPGLADFKPKYTSLFINNEFVDAKSGK-TFEFVNPANGKLLAKVAEGNRDDVDI 75

  Fly    72 AIDAAKQAYE-SKEWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKG-EVAYGN 134
            |::|||:|:: ..|||.:.|..|..||.:...|:|:....:|.:.:.::|||..|:.. ::....
 Worm    76 AVEAAKKAFKIGSEWRRMDASHRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISI 140

  Fly   135 AFVEWFAEEARRIYGEIVPSASPNREIIVMKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVV 199
            ....::|..|.:.:|:.:| ...:.......:|:||...|.|||||:.|...|...|||.|.|||
 Worm   141 KTFRYYAGYADKNHGKTIP-VGGDYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVV 204

  Fly   200 VKPSEDTPLTALAVAKLAVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLF 264
            :|.:..|||:||.||.|..:|..|:||:|:: ..:....|:......||..::|||||||||.:.
 Worm   205 MKVAVKTPLSALHVASLIKEAQFPEGVVNII-PGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIM 268

  Fly   265 RNSAD-GIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFV 328
            :.:|: .:|::.|||||.:|.|||..||:|:||..:..:.|.|.||.|.:.:|.||:..:||:||
 Worm   269 KAAAESNVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFV 333

  Fly   329 GQLKKRVEALKIGDGQGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAP 393
            .:.|:.||...|||....:...||.|:|.|...:..::|..:.:.|.::.||....|:| .|..|
 Worm   334 AKAKELVEKTVIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGDQG-YFVKP 397

  Fly   394 TIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEV 458
            ||..:|....::..||:||||:.:|||...||.::|||:|..|||....:.:|.:..:||..:..
 Worm   398 TIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDLNKALQVANTIRA 462

  Fly   459 GMVGVNEGIISAAEAPFGGVKESGVGREGSKHGIDDYVDIKYI 501
            |.|.||...:....|||||.|:||:|||..::|:..|.::|.:
 Worm   463 GSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	164/456 (36%)
alh-2	NP_503467.2	ALDH_F1-2_Ald2-like	34..507	CDD:143410	170/476 (36%)