Protein Alignment Ssadh and Aldh

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_313425.3
• Gene: Aldh / 1274323
• VectorBaseID: AGAMI1_004719
• Length: 515
• Species: Anopheles gambiae
• Alignment Length: 474
• Identity: 169/474 - (35%)
• Similarity: 269/474 - (56%)
• Gaps: 11/474 - (2%)

  Fly    33 VDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYE-SKEWRSLTAKDRSNL 96
            ::..|..||..| ||...||:|..||.::...|.||..:|:.||:.|:: ...||.:.|..|..|
Mosquito    39 INNEWHKSSTGK-TFPTVNPSNEKVIAEIQQGTKADIDQAVVAARDAFKLGSPWRRMDASKRGQL 102

  Fly    97 LKKWHKLIEQHSQEIAEIMTAESGKPINESKG-EVAYGNAFVEWFAEEARRIYGEIVPSASPNRE 160
            |.:...|:|:....:|.:.|.::|||...|.. :|....:.:.::|..|.:.:|:::|.   :.|
Mosquito   103 LYRLADLMERDRVYLASLETLDNGKPYFMSYNVDVPMAISNLRYYAGWADKNHGKVIPM---DGE 164

  Fly   161 IIV--MKQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKLAVDAGIP 223
            ..|  ..:|:||...|.|||||:.|...|.|.|||.|.|:::||:|.|.||||.:|:|..:||.|
Mosquito   165 FFVYTRHEPVGVCGQIIPWNFPILMAAWKFGPALATGNTIILKPAEQTSLTALYMAQLTKEAGFP 229

  Fly   224 KGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSA-DGIKRICLELGGNAPFIVF 287
            .||:|||.....|  |......|||..::|||||||||.:.:.|. ..:||..|||||.:|.|:.
Mosquito   230 PGVVNVVPGYGDA--GAALVDHPDVDKVAFTGSTEVGKKIQQGSGLSNLKRTTLELGGKSPNIIL 292

  Fly   288 DSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGP 352
            ..||::.||:.:....|.|.||.|.:.:|.|::|.:||:||.:..:|.:...:|:......:.||
Mosquito   293 SDADMKHAVETSHFGLFFNMGQCCCAGSRTFIEDKIYDEFVERSAERAKKRTVGNPFDLTTEHGP 357

  Fly   353 LINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSI 417
            .::..|::|:.|.::..:.:.|.::.||..:||....|..||:..||.....:..||:||||..:
Mosquito   358 QVDRAQYDKILGLIDTGKQQGARLVAGGSKVPDLPGYFIQPTVFADVQDDMTIAQEEIFGPVQQL 422

  Fly   418 IRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEAPFGGVKESG 482
            |||:..:|.:::||.|..|||...:|:::.:|..:.:.|..|.|.||...:.:|:|||||.|.||
Mosquito   423 IRFKSLDEVIERANKTDYGLAAAVFSKDIDKVNYLVQGLRAGTVWVNTYNVLSAQAPFGGYKMSG 487

  Fly   483 VGREGSKHGIDDYVDIKYI 501
            .|||..::|:..|.::|.:
Mosquito   488 HGRENGEYGLQAYTEVKSV 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	163/458 (36%)
Aldh	XP_313425.3	ALDH_F1AB_F2_RALDH1	30..509	CDD:143459	169/474 (36%)