Protein Alignment Ssadh and aldh1a2

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_571925.1
• Gene: aldh1a2 / 116713
• ZFINID: ZDB-GENE-011010-3
• Length: 518
• Species: Danio rerio
• Alignment Length: 485
• Identity: 166/485 - (34%)
• Similarity: 260/485 - (53%)
• Gaps: 23/485 - (4%)

  Fly    30 KALVDGAWVDSSNAKATFEVRNPANGAVIGKVPNMTVADAQKAIDAAKQAYE-SKEWRSLTAKDR 93
            |..::..|.||.:.| .|...|||.|..|..|.....||..||:.||:.|:. ...||.:.|.:|
Zfish    39 KIFINNEWHDSVSGK-VFPTYNPATGEKICDVQEADKADVDKAVQAARSAFSLGSVWRKMDASER 102

  Fly    94 SNLLKKWHKLIEQHSQEIAEIMTAESGKP-----INESKGEVAYGNAFVEWFAEEARRIYGEIVP 153
            ..||.|...|:|:.|..:|.:.:.:||||     ..:.:|.:.....:..|    |.:|:|..:|
Zfish   103 GKLLFKLADLVERDSAYLATLESLDSGKPFLPCFFVDLQGIIKTFRYYAGW----ADKIHGSTIP 163

  Fly   154 SASPNREIIVM--KQPIGVAALITPWNFPMAMITRKAGAALAAGCTVVVKPSEDTPLTALAVAKL 216
            .   :.|...:  .:||||...|.|||||:.|...|.|.||:.|.|||:||:|.||||.|.:..|
Zfish   164 I---DGEFFTLTRHEPIGVCGQIIPWNFPLVMTAWKLGPALSCGNTVVLKPAEQTPLTCLYLGAL 225

  Fly   217 AVDAGIPKGVINVVTTNKAAPIGDLFCKSPDVRGISFTGSTEVGKLLFRNSADG---IKRICLEL 278
            ..:||.|.||:|:: .......|........:..::||||||||||:  ..|.|   :||:.|||
Zfish   226 IKEAGFPPGVVNIL-PGYGPTAGAAISSHMGIDKVAFTGSTEVGKLI--QEAAGKSNLKRVTLEL 287

  Fly   279 GGNAPFIVFDSADIEKAVDGAMASKFRNCGQTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDG 343
            ||.:|.|:|..||.|.|::.|....|.|.||.|.:.:|.||::.:||:||.:..:|.:..|:|:.
Zfish   288 GGKSPNIIFADADFELALEQAHQGVFFNNGQCCTAGSRIFVEEPIYDEFVRRSVERAQRRKVGNP 352

  Fly   344 QGCDVQIGPLINEMQFNKVSGFVEDARSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSE 408
            .....:.||.::|.|..:|...::...::.|.:..||:....|| .|..||:.::|....::..|
Zfish   353 FDPTTEHGPQVSEEQQRRVLELIQSGITEGAKLECGGKAPATKG-FFVEPTVFSNVKDHMRIAKE 416

  Fly   409 EVFGPVVSIIRFRDEEEAVKKANDTRRGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGIISAAEA 473
            |:||||..|::|:..||.:::||:|..|||...::.::.:...::..::.|.|.:|.....:.:.
Zfish   417 EIFGPVQQIMKFKTIEEVIERANNTEYGLAAAVFTRDISKAMTISAAVQAGTVWINCYNAMSCQC 481

  Fly   474 PFGGVKESGVGREGSKHGIDDYVDIKYICM 503
            ||||.|.||.|||..:.|:.:|.::|.|.|
Zfish   482 PFGGFKMSGNGRELGEIGLKEYTELKTITM 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	159/464 (34%)
aldh1a2	NP_571925.1	ALDH_F1AB_F2_RALDH1	32..512	CDD:143459	166/485 (34%)