Protein Alignment Ssadh and Aldh3a2

DIOPT Version :10

• Sequence 1: NP_651408.1
• Gene: Ssadh / 43092
• FlyBaseID: FBgn0039349
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001318043.1
• Gene: Aldh3a2 / 11671
• MGIID: 1353452
• Length: 507
• Species: Mus musculus
• Alignment Length: 453
• Identity: 130/453 - (28%)
• Similarity: 219/453 - (48%)
• Gaps: 76/453 - (16%)

  Fly    77 KQAYESKEWRSLTAKDRSNLLKKWHKLIEQHSQEIAEIMTAESGKPINESKGEVAYGNAFVEWFA 141
            :||:.|  .||...:.|...|:...:::::..:||...:.|:.      ||.|:   ||    ::
Mouse     9 RQAFRS--GRSRPLRFRLQQLEALRRMVQEREKEILAAIAADL------SKSEL---NA----YS 58

  Fly   142 EEARRIYGEI---------VPSASPNR--------EIIVMKQPIGVAALITPWNFPMAMITRKAG 189
            .|...|.|||         :.||.|.:        |..|..:|:||..:|..||:|..:..:...
Mouse    59 HEVITILGEIDFMLGNLPELASARPAKKNLLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTMQPLV 123

  Fly   190 AALAAGCTVVVKPSEDTPLTALAVAKL-----------AVDAGIPKGVINVVTTNKAAPIGDLFC 243
            .|:|||...:|||||.:..||..:|:|           .|:.|||:      ||       :|..
Mouse   124 GAIAAGNAAIVKPSELSENTAKILAELLPQYLDQDLYAIVNGGIPE------TT-------ELLK 175

  Fly   244 KSPDVRGISFTGSTEVGKLLFRNSADGIKRICLELGGNAPFIVFDSADIEKAVDGAMASKFRNCG 308
            :..|  .|.:||:|.|||::...:|..:..:.|||||.:|..:....|::.|.......|:.|||
Mouse   176 QRFD--HILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDRDCDLDVACRRIAWGKYMNCG 238

  Fly   309 QTCVSANRFFVQDSVYDKFVGQLKKRVEALKIGDGQGCDVQIGP----LINEMQFNKVSGFVEDA 369
            |||::.:....:.|:.::.|.::|:.|:     |..|.:::..|    :||...|.::...:
Mouse   239 QTCIAPDYILCEASLQNQIVQKIKETVK-----DFYGENIKASPDYERIINLRHFKRLQSLL--- 295

  Fly   370 RSKKANIILGGQPLPDKGSLFYAPTIVTDVPPSAQLYSEEVFGPVVSIIRFRDEEEAVKKANDTR 434
              |...|..||:  .|:.:.:.||||:|||.|::::..||:|||::.|:..::.:||:...||..
Mouse   296 --KGQKIAFGGE--MDEATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAINFINDRE 356

  Fly   435 RGLAGYFYSENLQQVFRVAKRLEVGMVGVNEGII--SAAEAPFGGVKESGVGREGSKHGIDDY 495
            :.||.|.:|.|.:.:.||......|.|..|:.|:  :....|||||..||:|....|:..|.:
Mouse   357 KPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTF 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ssadh	NP_651408.1	ALDH_F5_SSADH_GabD	49..503	CDD:143421	130/453 (29%)
Aldh3a2	NP_001318043.1	ALDH_F3AB	5..444	CDD:143450	130/453 (29%)