DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and CPR4

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_009995.1	Gene:	CPR4 / 850433	SGDID:	S000000665	Length:	318	Species:	Saccharomyces cerevisiae

Alignment Length:	183	Identity:	34/183 - (18%)
Similarity:	59/183 - (32%)	Gaps:	70/183 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   519 DMEIAGELAGRVLIEVRSDAAPRMADNFGALVRHERG------------YGYRGCTVFQAWGGES 571
            :.::..||.|.|:        |:..:||..|....:.            |.||...:.:.:..:.
Yeast    65 EADLTFELYGTVV--------PKTVNNFAMLAHGVKAVIEGKDPNDIHTYSYRKTKINKVYPNKY 121

  Fly   572 IITG--------------DFESQNGRGGHSAFE---SRYFLPDETGLPAHRGTVGMRRGQRRQDR 619
            |..|              .|:.:|....|...|   ..||.||                   .:.
Yeast   122 IQGGVVAPDVGPFTVYGPKFDDENFYLKHDRPERLAMAYFGPD-------------------SNT 167

  Fly   620 SGFV------GSQFRLVLNEMRSFTAIFGFIVQGI-ELVDRIA-ASGNALGRP 664
            |.|:      |::      |:...:.:||.|..|: :|:|.|. ...:..|:|
Yeast   168 SEFIITTKADGNE------ELDGKSVVFGQITSGLDQLMDAIQYTETDEYGKP 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	34/183 (19%)
CPR4	NP_009995.1	cyclophilin	67..219	CDD:238194	34/181 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900