DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and Ppil6

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_082706.1	Gene:	Ppil6 / 73075	MGIID:	1920325	Length:	313	Species:	Mus musculus

Alignment Length:	181	Identity:	47/181 - (25%)
Similarity:	71/181 - (39%)	Gaps:	39/181 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 FLDMEIAGELA--GRVLIEVRSDAAPRMADNFGALVRHERGYGYRGC-----------TVFQAWG 568
            |:.::|..:|:  ||::.|:..||.||...||..|.....|:..||.           .|...|
Mouse   145 FVYLDICIDLSPIGRLIFELYCDACPRTCTNFQVLCTGTSGFSERGTKLHYKDSIFHRVVQNGW- 208

  Fly   569 GESIITGDFESQNGRGGHS----AFESRYFLPDETGLPAH-RGTVGM-RRGQRRQDRSGFVGSQF 627
               |..||.....|..|.|    .||...|     .:|.: ||.:|| .:|....      ||||
Mouse   209 ---IQGGDIVQGRGDDGESIYGPTFEDENF-----SIPHNKRGVLGMVNKGHHTN------GSQF 259

  Fly   628 RLVLNEM----RSFTAIFGFIVQGIELVDRIAASGNALGRPALRSIIRNCG 674
            .:.|...    :.:.| ||.:::|..::.::........||.|...|.:.|
Mouse   260 YITLQAAPYLDKKYVA-FGQLIEGTHVLKQLELVPTENERPLLLCSIADSG 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	46/179 (26%)
Ppil6	NP_082706.1	cyclophilin	146..309	CDD:294131	45/178 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900