DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and Ppib

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_071981.1	Gene:	Ppib / 64367	RGDID:	620312	Length:	208	Species:	Rattus norvegicus

Alignment Length:	213	Identity:	55/213 - (25%)
Similarity:	95/213 - (44%)	Gaps:	24/213 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   473 AILVNSVEPQLIGQQSHDHHRQDGGTSSSVSIVRQPIVHCYPIYFLDMEIAGELAGRVLIEVRSD 537
            |::|.||...|:...|..:.::.|   ..|::         .:|| |.:|..|..|||...:...
  Rat     8 ALIVGSVVFLLLPGPSVANDKKKG---PKVTV---------KVYF-DFQIGDEPVGRVTFGLFGK 59

  Fly   538 AAPRMADNFGALVRHERGYGYRGCTVFQAWGGESIITGDFESQNGRGGHSAFESRYFLPDETGLP 602
            ..|:..|||.||...|:|:||:.....:......|..|||...:|.||.|.:..|:  |||....
  Rat    60 TVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERF--PDENFKL 122

  Fly   603 AHRGTVGMRRGQRRQDRSGFVGSQFRLVLNEMRSFT----AIFGFIVQGIELVDRIA-ASGNALG 662
            .|.|...:......:|.:   |||| .:.....|:.    .:||.:::|:::|.::. ...::..
  Rat   123 KHYGPGWVSMANAGKDTN---GSQF-FITTVKTSWLDGKHVVFGKVLEGMDVVRKVENTKTDSRD 183

  Fly   663 RPALRSIIRNCGEYHLNQ 680
            :|....||.:||:..:.:
  Rat   184 KPLKDVIIVDCGKIEVEK 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	45/164 (27%)
Ppib	NP_071981.1	cyclophilin_ABH_like	37..195	CDD:238907	45/164 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900