DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and RANBP2

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_005264059.1	Gene:	RANBP2 / 5903	HGNCID:	9848	Length:	3258	Species:	Homo sapiens

Alignment Length:	178	Identity:	49/178 - (27%)
Similarity:	84/178 - (47%)	Gaps:	10/178 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   502 VSIVRQPIVHCYPIYFLDMEIAGELAGRVLIEVRSDAAPRMADNFGALVRHERGYGYRGCTVFQA 566
            ||:..:......|:.|.|:...||..||:.:|:.|:..||.|:||.||...|:|:|::. ::|..
Human  3086 VSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFGFKN-SIFHR 3149

  Fly   567 WGGESIIT-GDFESQNGRGGHSAFESRYFLPDETGLPAHRGTVGMRRGQRRQDRSGFVGSQFRLV 630
            ...:.:.. ||....:|.||.|.:..::  .||.....|.|...:....:.|:.:   .|||.:.
Human  3150 VIPDFVCQGGDITKHDGTGGQSIYGDKF--EDENFDVKHTGPGLLSMANQGQNTN---NSQFVIT 3209

  Fly   631 LNEMRSFT---AIFGFIVQGIELVDRIAASGNALGRPALRSIIRNCGE 675
            |.:.....   .:|||:..|::.|.:|.:.|:..|....|..|..||:
Human  3210 LKKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVCRRITITECGQ 3257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	45/163 (28%)
RANBP2	XP_005264059.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900