DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and ppil6

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001018433.1	Gene:	ppil6 / 553623	ZFINID:	ZDB-GENE-050522-70	Length:	293	Species:	Danio rerio

Alignment Length:	176	Identity:	52/176 - (29%)
Similarity:	74/176 - (42%)	Gaps:	30/176 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   517 FLDMEIAGELAGRVLIEVRSDAAPRMADNFGALVRHERG-------YGYRGCTVF-----QAWGG 569
            ::|:|..||..||:|.|:.||..|:...||.||...|.|       ..|:| :||     ..|
Zfish   126 YMDIENGGEAVGRLLFELFSDVCPKTCRNFKALCTGEAGLSKSNLELSYKG-SVFHRVVPNGW-- 187

  Fly   570 ESIITGDFE-SQNGRGGHSAFESRYFLPDETGLPAH--RGTVGMRRGQRRQDRSGFVGSQFRLVL 631
              |..||.. .:.|.||.|.:...:  .||..:.:|  ||.:||.......:     ||||.:.|
Zfish   188 --IQGGDISPEKKGTGGESIYGPTF--EDENFVISHNKRGILGMANQGAHSN-----GSQFYITL 243

  Fly   632 NE---MRSFTAIFGFIVQGIELVDRIAASGNALGRPALRSIIRNCG 674
            ..   |......||.:.:|.:::.|:.|......||.....|..||
Zfish   244 QPATWMDQKYVAFGQLAEGTDVLKRLEAVPTYNERPKQDCKIVACG 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	50/174 (29%)
ppil6	NP_001018433.1	cyclophilin	125..289	CDD:294131	50/174 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900