DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and ppie

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001017678.1	Gene:	ppie / 550373	ZFINID:	ZDB-GENE-050417-167	Length:	302	Species:	Danio rerio

Alignment Length:	176	Identity:	53/176 - (30%)
Similarity:	86/176 - (48%)	Gaps:	28/176 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 PIYFLDMEIAGELAGRVLIEVRSDAAPRMADNFGALVRHERGYGYRGCTV------FQAWGGESI 572
            |..::|::|..:.|||:...:|:|..|..|:||..|..||:|:|::|.:.      |...|
Zfish   141 PQVYMDIKIGNKPAGRLRFLLRADVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQG---- 201

  Fly   573 ITGDFESQNGRGGHS----AFESRYFLPDETGLPAHRGTVGMRRGQRRQDRSGFVGSQFRLVLNE 633
              |||.:.||.||.|    .||...|:...|    |.|.:.|.......:     ||||.:.:::
Zfish   202 --GDFTNHNGTGGKSIYGRKFEDENFVLKHT----HAGQLSMANSGPNTN-----GSQFFITVDK 255

  Fly   634 ---MRSFTAIFGFIVQGIELVDRIAASGNALGRPALRSIIRNCGEY 676
               :.....:||.:.:|::::..:.|.|...|:|..:.||.|||||
Zfish   256 TDWLDGKHVVFGELTEGMDVLRAMEAQGTKDGKPKQKVIISNCGEY 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	49/172 (28%)
ppie	NP_001017678.1	RRM_PPIE	8..80	CDD:240793
ppie	NP_001017678.1	cyclophilin_ABH_like	141..299	CDD:238907	49/172 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000