DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and MGC79670

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001007509.1	Gene:	MGC79670 / 493235	XenbaseID:	XB-GENE-5802720	Length:	526	Species:	Xenopus tropicalis

Alignment Length:	323	Identity:	66/323 - (20%)
Similarity:	113/323 - (34%)	Gaps:	83/323 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ELKSLLSCGLCHRPY-DLATGLLPQELACRHSFCKKCVQR--NTDHNSSECICNLCGYRTQLDGQ 70
            :|:..|:|.:|...| |      |..|.|.|:||..|::.  .|...|....|..|  |.:
Frog     5 DLREELNCSICLNIYAD------PVTLKCGHNFCLACIKSVLATQKGSGAYSCPEC--RAE---- 57

  Fly    71 QLPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEE------------APSSPS------ 117
                       .||.|||.....:.:.:.:..||.....:.            ||::.|
Frog    58 -----------FRERPALQRNMKLSNIAERFRSTRSTQPKRTGIFCTYCIHSPAPAAKSCLLCEA 111

  Fly   118 ---KNWV-------EDINVESFLATSAEHCFIHAMPNSTWCHNCQRLLCRACSDVPLHQDHILVR 172
               :|.|       |.:..:...:.:...|.:|......:|......:|.:|..:..|:.|
Frog   112 HLCENHVLVHSKSPEHVLTDPTTSLNNRKCSVHKEVMKYYCPEDAVCICVSCCVLGEHRGH---- 172

  Fly   173 QVDYHDLISQLLNSELRKIKSTAVHAKELATHEMDLLRELCEACYRVQ-LHVKREMLEHHSSMVA 236
            ||       :|||....|.|....:..|..|.:.|      :|..|:| |...|..::..::.|:
Frog   173 QV-------ELLNEATEKKKKRLRNILENLTSKQD------QAQIRIQNLQEHRRDVQDKAAAVS 224

  Fly   237 ---ASMIGWHR-----LAERDLHRVGRLTGAKMLQV---LAHLATQRQRYERQLDQVHFQCRM 288
               .::.|..|     |.:|.|..:.|.....:|.|   :..|..|::....::..:...|.|
Frog   225 DQVTALFGDIREQLEALEKRVLCEISRQEEQALLHVSDLIQQLEIQKEELSAKMHHIEALCNM 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	13/45 (29%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
MGC79670	NP_001007509.1	RING_Ubox	9..55	CDD:388418	16/53 (30%)
		Bbox_SF	92..132	CDD:381767	6/39 (15%)
		Bbox2_TRIM16-like	139..185	CDD:380827	13/56 (23%)
		BBC	184..301	CDD:128778	22/110 (20%)
		SPRY_PRY_C-I_2	357..525	CDD:293949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I5302
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960