DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and ppid

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001002065.1	Gene:	ppid / 415155	ZFINID:	ZDB-GENE-040625-34	Length:	371	Species:	Danio rerio

Alignment Length:	184	Identity:	52/184 - (28%)
Similarity:	78/184 - (42%)	Gaps:	36/184 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 PIYFLDMEIAGELAGRVLIEVRSDAAPRMADNFGALVRHERGYG--------YRGCTVFQAWGGE 570
            |..|.|:||..|..|||:.|:.:|..|:.|:||.||...|:|.|        ::||...:.....
Zfish    16 PRVFFDVEIGAERVGRVVFELFADVVPKTAENFRALCTGEKGVGKSTGKPLHFKGCPFHRIIKSF 80

  Fly   571 SIITGDFESQNGRGGHSAFESRYFLPDETGLPAHRGTVGMRRGQRRQDRSGFV----------GS 625
            .|..|||.:|||.||.|.:..::  .||.....|             ||.|.:          ||
Zfish    81 MIQGGDFSNQNGTGGESIYGDKF--EDENFHYKH-------------DREGLLSMANAGPNTNGS 130

  Fly   626 QFRLV---LNEMRSFTAIFGFIVQGIELVDRIAASGNALGRPALRSIIRNCGEY 676
            ||.:.   ...:.....:||.:::|:.:|..:.|.......|....:|..|||:
Zfish   131 QFFITTVPTPHLDGKHVVFGQVLKGMGVVKMLEAMETKEDNPVKPCVIAECGEH 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	49/180 (27%)
ppid	NP_001002065.1	cyclophilin_ABH_like	16..182	CDD:238907	49/180 (27%)
		TPR_11	223..304	CDD:290150
		TPR repeat	223..268	CDD:276809
		TPR_12	271..340	CDD:290160
		TPR repeat	273..303	CDD:276809
		TPR repeat	308..336	CDD:276809
		TPR_1	309..341	CDD:278916
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900