DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and Trim11

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_006246567.1	Gene:	Trim11 / 360534	RGDID:	1305448	Length:	467	Species:	Rattus norvegicus

Alignment Length:	389	Identity:	85/389 - (21%)
Similarity:	139/389 - (35%)	Gaps:	99/389 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MESIQVPKELKSLLSCGLCHRPYDLATGLLPQELACRHSFCKKCVQRNTDHNSSECICNLCGYRT 65
            |.:..:...|:...:|.:|   .|..|.  |....|.|:||::|::|..........|..|
  Rat     1 MAAPDLSTNLQEEATCAIC---LDYFTD--PVMTDCGHNFCRECIRRCWGQPEGPYACPEC---- 56

  Fly    66 QLDGQQLPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEEAPSSPSKNWVEDINVESFL 130
                             ||:.|    :..|..:...:...||:....|.||....|
  Rat    57 -----------------REVSA----QRNLRPNRPLAKMAEMARRLHPPSPVPQGV--------- 91

  Fly   131 ATSAEHCFIHAMPNSTWCHNCQRLLCRAC--SDVPLHQDHILVRQVDYHDLISQLLNS--ELRKI 191
                  |..|..|.:|:|.:...|||..|  |:...|:...|....|  ||..:|..|  .|||.
  Rat    92 ------CAAHREPLTTFCGDDLSLLCPTCERSEHWAHRVRPLQEAAD--DLKGRLEKSLEHLRKQ 148

  Fly   192 KSTAVHAKELATHEMDLLRELCEACYRVQL----HVKREMLEHHSSMVAASMIGWHRLAERDLHR 252
            ...|:..:..|.....|.:::.|:..:..|    .::|.:.|....::       .:|.|.:|..
  Rat   149 MEDAMLFQAQAEETCALWQKMVESQRQNVLGEFERLRRLLAEEEQQLL-------QKLEEEELEV 206

  Fly   253 VGRL-TGAKMLQVLAHLATQRQRYERQLDQVHFQCRMQAAIQENGMQVLDFETLNNRIARLRSHR 316
            :.|| .||      |.|..|..:....:.::..:|::.|.    |:    .:.:.:.:.|::..:
  Rat   207 LPRLREGA------ARLGQQSTQLAALVSELESRCQLPAL----GL----LQDIKDALCRVQDVK 257

  Fly   317 --RPGAIPANVGPPQALILTNYCVYAYWCEMQREMIPPRHR---NLTPD---PEL-LPEPRRAV 371
              .|..:|        :.|...|......|..|     |.|   .|.||   ||| |.|.||:|
  Rat   258 LQPPAVVP--------MELRTVCRVPGLVETLR-----RFRGDITLDPDTANPELVLSEDRRSV 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	11/42 (26%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
Trim11	XP_006246567.1	zf-C3HC4_4	16..56	CDD:291880	12/44 (27%)
		zf-B_box	87..127	CDD:279037	12/54 (22%)
		SPRY_PRY_TRIM11	287..455	CDD:293983	11/22 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	47	1.000	Inparanoid score	I5392
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050