DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5071 and ppiaa

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_997923.1	Gene:	ppiaa / 336612	ZFINID:	ZDB-GENE-030131-8556	Length:	164	Species:	Danio rerio

Alignment Length:	166	Identity:	49/166 - (29%)
Similarity:	86/166 - (51%)	Gaps:	10/166 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 PIYFLDMEIAGELAGRVLIEVRSDAAPRMADNFGALVRHERGYGYRGCTVFQAWGGESIITGDFE 578
            |..|.|:...|...|||::|:|:|..||.|:||..|...:.||||:|.:..:...|.....|||.
Zfish     4 PKVFFDLTAGGNPVGRVVMELRADVVPRTAENFRQLCTGQPGYGYKGSSFHRVIPGFMCQGGDFT 68

  Fly   579 SQNGRGGHSAFESRYFLPDETGLPAHRGTVGMRRGQRRQDRSGFVGSQFRLVLNEMRSFT----A 639
            :.||.||.|.:.:::  .||.....|.|...:.......:.:   |||| .:...:.|:.    .
Zfish    69 NHNGTGGKSIYGNKF--ADENFNLKHTGAGCLSMANAGPNTN---GSQF-FICTALTSWLDGKHV 127

  Fly   640 IFGFIVQGIELVDRIAASGNALGRPALRSIIRNCGE 675
            :||.:|:|::::.::...|::.|:.:.:.||.:||:
Zfish   128 VFGQVVEGLDVIKKVEGFGSSSGKTSAKIIIADCGQ 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	47/163 (29%)
ppiaa	NP_997923.1	cyclophilin_ABH_like	4..162	CDD:238907	47/163 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900