DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and Trim69

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_006234918.2	Gene:	Trim69 / 311373	RGDID:	1305074	Length:	577	Species:	Rattus norvegicus

Alignment Length:	426	Identity:	82/426 - (19%)
Similarity:	144/426 - (33%)	Gaps:	142/426 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VPKELKSLLSCGLCHRPY-DLATGLLPQELACRHSFCKKCVQRNTDHNSSECIC----NLCGYRT 65
            |.:::.:.|.|.||:..: |      |..|.|.|:||:.|:|......:.|..|    .||.|
  Rat   109 VIQDITTELHCPLCNDWFRD------PLMLTCGHNFCQACIQNYWKMQAKETFCPECKMLCQY-- 165

  Fly    66 QLDGQQLPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEEAPSSPSKNWVEDINVESFL 130
                    .:.|...:|.:|...|....:|              :..|..|.
  Rat   166 --------SNCTFNLVLEKLVEKIKRLPLL--------------KGHPQCPE------------- 195

  Fly   131 ATSAEHCFIHAMPNSTWCHNCQRLLCRACSDVPL----HQDHILVRQVDYHDLISQLLNSEL--- 188
              ..|:..:.:.|:.       :::|..|.|..|    .:|.:.:.:.      .:....||
  Rat   196 --HGENLKLFSKPDG-------KMICFQCKDARLSMGQSKDFLQISEA------VRFFTEELAIY 245

  Fly   189 -RKIKSTAVHAKELATHEMDLLRELCEACYRVQLHVKREMLEHHSSMVAASMIGWHRLAE---RD 249
             .::::|....:.|.|.:.|.:....:...::|.::..|.|:.|..:        |...:   .|
  Rat   246 QSQLQTTLKELQSLRTMQKDAIAAYKDNKIQLQQNLSLEFLKLHQFL--------HNKEKDILND 302

  Fly   250 LHRVGRLTGAKMLQVLAHLATQRQRYERQLDQVHFQC----RMQAAIQENGMQVLDFETLNNRIA 310
            |...|::...:|              :..|:|:..||    .|.|.||....|...|:.|.: |.
  Rat   303 LRDEGKVLNEEM--------------DANLNQIQEQCLLAKDMLANIQARMEQQNSFDFLTD-IT 352

  Fly   311 RLRSHRRPG---AIPANV-----------GPPQALILTNYCVYAYWCEMQREMIPPRHRNLTPDP 361
            :|..:...|   .:|..:           ||.|         |..|.||| .::.|....||.||
  Rat   353 KLLENMEKGMKTLVPRQLISKKLSLGRFKGPIQ---------YTIWREMQ-SILSPGPSQLTLDP 407

  Fly   362 E------LLPEPRRAVV-----------PPHFNNSL 380
            :      :|...|.:|.           |..|::|:
  Rat   408 KTAHPNLVLSNSRTSVCHGDVKQVMPDDPERFDSSV 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	14/47 (30%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
Trim69	XP_006234918.2	zf-C3HC4_4	119..159	CDD:291880	14/45 (31%)
Trim69	XP_006234918.2	SPRY	389..574	CDD:295394	15/56 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	47	1.000	Inparanoid score	I5392
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050