DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5071 and Trim39

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_017457122.1	Gene:	Trim39 / 309591	RGDID:	1303115	Length:	608	Species:	Rattus norvegicus

Alignment Length:	405	Identity:	82/405 - (20%)
Similarity:	146/405 - (36%)	Gaps:	121/405 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MESIQVPKELKSLLSCGLCHRPYDLATGLLPQELACRHSFCKKCVQRNTDHNSSECICNLC---- 61
            :|::||.      .||.:|     |.....|..:.|.|:|||.|:.|..:....:..|.:|
  Rat   132 LENLQVE------ASCSVC-----LEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTS 185

  Fly    62 GYRTQLDGQQLPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEEAPSSPSKNWVEDINV 126
            .||:....:||...|.|.                    |:..|::..|.:
  Rat   186 RYRSLRPNRQLGSMVEIA--------------------KQLQTVKRKIRD--------------- 215

  Fly   127 ESFLATSAEHCFIHAMPNSTWCHNCQRLLCRACSDVPLHQDHILVRQVD----YHDLISQLLNSE 187
            ||.       |..|..|.|.:|:..|..:|..|:....|:.|.:|...|    |.:.:.:.|...
  Rat   216 ESL-------CSQHHEPLSLFCYEDQEAVCLICAISHTHRAHTVVPMDDATQEYKEKLQKCLEPL 273

  Fly   188 LRKIKS-TAVHAKE----------LATHEMDLLRELCEACYRVQLHVKREMLEHHSSMVAASMIG 241
            .:|::. |...|.|          :.:....:|:|..|      ||  |.:.|...::::
  Rat   274 EQKLQEITCCKASEERKPGELKRLVESRRQQILKEFEE------LH--RRLDEEQQTLLS----- 325

  Fly   242 WHRLAERDLHRVGRLTGAKMLQVLAHLATQRQRYERQLDQVHFQCRMQAAIQENGMQVL-DFETL 305
              ||.|.:...:.||.     :..|||.      :|:.|..|....::....::|.::| |.::.
  Rat   326 --RLEEEEQDILQRLR-----ENAAHLG------DRRRDLAHLAAEVEGKCLQSGFEMLKDVKST 377

  Fly   306 NNRIARLRSHRRPGA---IPANVG--PPQALIL---TNYCVYAYWCEMQREMIPPRHRNLTPDPE 362
            ..:..::::......   :..|..  |.|...|   ....:...|      ::||  .::|.|||
  Rat   378 LEKCEKVKTMEVTSVSIELEKNFSHFPRQYFALRKILKQLIAPLW------LLPP--ADVTLDPE 434

  Fly   363 ------LLPEPRRAV 371
                  :|.|.|::|
  Rat   435 TAHPNLVLSEDRKSV 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	11/42 (26%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
Trim39	XP_017457122.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	47	1.000	Inparanoid score	I5392
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050