DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and Ppie

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001382655.1	Gene:	Ppie / 298508	RGDID:	1311411	Length:	301	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	56/174 - (32%)
Similarity:	88/174 - (50%)	Gaps:	24/174 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   514 PIYFLDMEIAGELAGRVLIEVRSDAAPRMADNFGALVRHERGYGYRGCTV------FQAWGGESI 572
            |..::|::|..:.|||:.:.:|||..|..|:||..|..||:|:|::|.:.      |...|
  Rat   140 PQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQG---- 200

  Fly   573 ITGDFESQNGRGGHSAFESRYFLPDETGLPAHRGTVGMRRGQRRQDRSG--FVGSQFRLVLNE-- 633
              |||.:.||.||.|.:..::  .||..:..|.|.     |......||  ..||||.|..::
  Rat   201 --GDFTNHNGTGGKSIYGKKF--DDENFILKHTGP-----GLLSMANSGPNTNGSQFFLTCDKTD 256

  Fly   634 -MRSFTAIFGFIVQGIELVDRIAASGNALGRPALRSIIRNCGEY 676
             :.....:||.|..|::::.:|.|.|:..|:|..:.||.:||||
  Rat   257 WLDGKHVVFGEITDGLDVLRQIEAQGSKDGKPKQKVIIADCGEY 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	52/170 (31%)
Ppie	NP_001382655.1	RRM_PPIE	8..82	CDD:409783
Ppie	NP_001382655.1	cyclophilin_ABH_like	140..298	CDD:238907	52/170 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900