DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and LOC105945814

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_031754251.1	Gene:	LOC105945814 / 105945814	-ID:	-	Length:	1127	Species:	Xenopus tropicalis

Alignment Length:	311	Identity:	67/311 - (21%)
Similarity:	110/311 - (35%)	Gaps:	98/311 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ELKSLLSCGLCHRPYDLATGLLPQELACRHSFCKKCVQR--NTDHNSSECICNLCGYRTQLDGQQ 71
            :|::.|:|.:|     |:....|..|.|.|::|:.|:.|  .|...|:...|..|
Frog    49 DLRAELNCSIC-----LSVYTDPVTLPCGHNYCRGCIGRLLGTSEGSAGYSCPEC---------- 98

  Fly    72 LPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEEAPSSP--SKNWVEDINVESFLATSA 134
                                ||                 |.|..|  |:|......||.||:|..
Frog    99 --------------------RA-----------------EYPERPTLSRNRTLGNIVEQFLSTHP 126

  Fly   135 EH---------CFIHAMPNSTWCHNCQRLLCRACSDVPLHQDHILVRQVDYHDLISQLLNSELRK 190
            ||         |....:|::..|..|:..||.|         |:.|.......::::...|.::
Frog   127 EHDGTGIYCTYCINSPVPSAKSCLLCEASLCDA---------HVRVHSKSAEHVLTEPTASFIK- 181

  Fly   191 IKSTAVHAKELATHEMDLLRELCEAC--------YRVQL---------HVKREMLEHHSSMVAAS 238
             :..:.|.|.|..|..:....:|.:|        :||:|         ...|::||:.|.:...:
Frog   182 -RKCSAHHKVLEYHCCEDGAPICVSCCLAGEHRGHRVELLSEASEKKKETLRKVLENLSPVGEDT 245

  Fly   239 MIGWHRLAERDLHRVGRLTGAKMLQVLAHLATQRQRYE----RQLDQVHFQ 285
            ..|..||.|| |.:|..:...:..:|.|..:..|:..|    |.|..:..|
Frog   246 ERGAQRLQER-LRKVEEVAAGETERVTALFSGIREELETLEMRLLSDISMQ 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	12/44 (27%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
LOC105945814	XP_031754251.1	PEX10	<6..103	CDD:227861	19/105 (18%)
		RING_Ubox	53..99	CDD:418438	15/80 (19%)
		Bbox_SF	135..175	CDD:412124	9/48 (19%)
		Bbox2_TRIM16-like	182..228	CDD:380827	9/45 (20%)
		BBC	227..354	CDD:128778	18/70 (26%)
		SPRY_PRY_C-I_2	404..569	CDD:293949
		PEX10	<576..668	CDD:227861
		RING_Ubox	622..667	CDD:418438
		Bbox_SF	703..743	CDD:412124
		Bbox2_TRIM16-like	750..795	CDD:380827
		BBC	794..907	CDD:128778
		SPRY_PRY_C-I_2	955..1126	CDD:293949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I5302
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050