DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and LOC100491243

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_012809394.2	Gene:	LOC100491243 / 100491243	-ID:	-	Length:	526	Species:	Xenopus tropicalis

Alignment Length:	333	Identity:	74/333 - (22%)
Similarity:	114/333 - (34%)	Gaps:	126/333 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ELKSLLSCGLCHRPYDLATGLLPQELACRHSFCKKCV--QRNTDHNSSECICNLCGYRTQLDGQQ 71
            :|:..|||.:|     |:....|..|.|.|:||..|:  ..:|...|....|..|..:.|
Frog     5 DLRDELSCSIC-----LSVYTDPVTLPCGHNFCHGCIGGLLDTQEGSGGYSCPECRAKFQ----- 59

  Fly    72 LPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEEAPSSPSKNWVEDINV-ESFLATSAE 135
                        |.|||           :|::|:.                  |: |.|.:|..|
Frog    60 ------------ERPAL-----------QRNTTLG------------------NLAELFFSTHPE 83

  Fly   136 H---------CFIHAMPNSTWCHNCQRLLCRACSDVPLHQ---DHILVRQVDYHDLISQLLNSEL 188
            |         |....:|.:..|..|:..||.|  .|.:|.   :|:|...            :.|
Frog    84 HDGTGIYCTYCINSPVPAAKSCILCEASLCDA--HVRVHSKSAEHVLTEP------------TAL 134

  Fly   189 RKIKSTAVHAKELATHEMDLLRELCE--ACYRVQLHVKREMLEHHSSMVAASMIGWHRLAERDLH 251
            ..|| .:||.|.|..:       .||  ||.                .|:..:.|.||     .|
Frog   135 ENIK-CSVHHKFLEYY-------CCEDGACI----------------CVSCCLAGEHR-----GH 170

  Fly   252 RVGRLTGAK------MLQVLAHLATQRQRYER---QLDQVHFQCRMQAAIQENGMQVL------D 301
            ||..|:.|.      :.:||.:|:.:|:..||   :|.:...:...:||.:...:..|      :
Frog   171 RVELLSEASEKKKETLRKVLENLSPEREETERGAQRLLESWREVEEKAAAETERVTALFRGIREE 235

  Fly   302 FETLNNRI 309
            .|.|..|:
Frog   236 LEALEKRL 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	12/44 (27%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
LOC100491243	XP_012809394.2	RING_Ubox	10..55	CDD:418438	15/49 (31%)
		Bbox_SF	91..131	CDD:412124	11/41 (27%)
		Bbox2_TRIM16-like	138..183	CDD:380827	18/73 (25%)
		BBC	182..293	CDD:128778	13/62 (21%)
		SPRY_PRY_C-I_2	357..524	CDD:293949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I5302
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050