DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5071 and trim25l

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_002942762.2	Gene:	trim25l / 100490741	XenbaseID:	XB-GENE-17329851	Length:	525	Species:	Xenopus tropicalis

Alignment Length:	338	Identity:	68/338 - (20%)
Similarity:	109/338 - (32%)	Gaps:	114/338 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ELKSLLSCGLCHRPYDLATGLLPQELACRHSFCKKCVQR--NTDHNSSECICNLCGYRTQLDGQQ 71
            :|:..|:|.:|...|.     .|..|.|.|:||:.|:.|  :|...:....|..|       ..:
Frog     6 DLREELNCSVCLSIYS-----DPIMLPCGHNFCQGCIGRVLDTQEGTGVYTCPEC-------RAE 58

  Fly    72 LPQSVTIMYLLRELPALILGRAMLDF---------------------------SYKRSSTIEMSI 109
            .|          |.|||...|.:.:.                           :.|.....|.|:
Frog    59 YP----------ERPALQRNRTLGNIAERFLCAQPGPGGTGIYCTYCIHSPVAAAKSCLLCEASL 113

  Fly   110 EEAPSSPSKNWVEDINVESFLATSAEHCFIHAMPNSTWCHNCQRLLCRACSDVPLHQDHILVRQV 174
            .|:.........|.:.||...|.....|..|..|...:|:.....:|.:|.....|:.|.:
Frog   114 CESHVRVHSRSAEHVLVEPTTAPEKRKCSAHGEPLKYYCYEDSACICASCCLGGQHKRHRV---- 174

  Fly   175 DYHDLISQ------------LLNSEL---------RKIKSTAVHAKELATHEMD----LLRELCE 214
               :|:|:            |||..|         :|::...|..:|.|..|||    |..::
Frog   175 ---ELLSEASDRKKEQLRKVLLNLPLMIEETERGAQKLQERRVQMQEQAAGEMDRVVALFADI-- 234

  Fly   215 ACYRVQLHVKREMLEHHSSMVAASMIGWHRLAERDLHRVGR----LTGAKMLQVLAHLATQRQRY 275
                      ||.||              .|..|.|..:.|    || |:..:::..|..:::..
Frog   235 ----------RERLE--------------ALERRVLSEIARQEEELT-ARASELIHQLEIKKEEL 274

  Fly   276 ERQLDQVHFQCRM 288
            .|::.|....|.|
Frog   275 SRKILQTEELCNM 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	12/44 (27%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
trim25l	XP_002942762.2	RING_Ubox	10..56	CDD:418438	15/57 (26%)
		Bbox_SF	92..132	CDD:412124	6/39 (15%)
		Bbox2_TRIM16-like	139..185	CDD:380827	10/52 (19%)
		BBC	184..295	CDD:128778	28/131 (21%)
		SPRY_PRY_C-I_2	352..514	CDD:293949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I5302
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050