DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5071 and LOC100489697

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_002940232.3	Gene:	LOC100489697 / 100489697	-ID:	-	Length:	546	Species:	Xenopus tropicalis

Alignment Length:	411	Identity:	79/411 - (19%)
Similarity:	125/411 - (30%)	Gaps:	168/411 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ELKSLLSCGLCHRPYDLATGLLPQELACRHSFCKKCV--QRNTDHNSSECICNLCGYRTQLDGQQ 71
            :|:..|||.:|     |:....|..|.|.|:||:.|:  ...|...|....|..|....|
Frog     5 DLRDELSCSIC-----LSIYTDPVSLPCGHNFCRGCIGLVLGTQEGSGAYSCPECRAEYQ----- 59

  Fly    72 LPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEEAPSSPSKNWVEDINVESFLATSAE- 135
                        |.|||...||:.:.:                            |.|..|..|
Frog    60 ------------ECPALPRNRALGNIA----------------------------ERFRPTETEP 84

  Fly   136 --------HCFIHAMPNSTWCHNCQRLLCRACSDVPLHQDHILVRQVDYHDLISQLLNSELRKIK 192
                    :|.:..:|.:..|..|:...|                            |..||...
Frog    85 GETGIFCTYCLLSPVPAAKSCLLCEASFC----------------------------NKHLRGHS 121

  Fly   193 STAVHAKELATHEMDLLRELCEACYRVQLHVKREMLEHHSSM------VAASMIGWHRLAERDLH 251
            .:|.|.  |.......:...|.        |..::||:|..:      |:..:.|.||     .|
Frog   122 QSAEHV--LTEPTASFMGRKCS--------VHHKVLEYHCCVDSACICVSCCLAGGHR-----GH 171

  Fly   252 RVGRLTGA------KMLQVLAHLATQRQRYERQLDQVHFQCRMQAAIQENGMQVLDFETLNNRIA 310
            ||..|:.|      |:.:||..|:::|:..||                  |.|
Frog   172 RVELLSEASEKKKEKLRKVLEKLSSEREETER------------------GAQ------------ 206

  Fly   311 RLRSHRRPGAIPANVGPPQALILTNYCVYAYWCEMQREMIPPRHRNLTPDPELLPEPRRAVVPPH 375
            ||:..||...|.| .|                   :|:.:....|::..:.|.|  .:|.:....
Frog   207 RLQERRRESEIKA-AG-------------------ERKRVTALFRSIREELEAL--EKRLLSDIS 249

  Fly   376 FNNSLREVELLDYVQQIELEQ 396
            .......::|.|.:||:|:::
Frog   250 RQREELSLQLKDLIQQLEIKK 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	12/44 (27%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
LOC100489697	XP_002940232.3	RING_Ubox	9..55	CDD:418438	15/50 (30%)
		Bbox_SF	91..131	CDD:412124	11/69 (16%)
		Bbox2_TRIM16-like	138..184	CDD:380827	14/58 (24%)
		BBC	183..309	CDD:128778	26/140 (19%)
		SPRY_PRY_C-I_2	359..526	CDD:293949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I5302
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960