DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5071 and LOC100489639

DIOPT Version :9

Sequence 1:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	XP_002939598.3	Gene:	LOC100489639 / 100489639	-ID:	-	Length:	465	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	61/296 - (20%)
Similarity:	95/296 - (32%)	Gaps:	85/296 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ELKSLLSCGLCHRPYDLATGLLPQELACRHSFCKKCVQRNTDHN---SSECICNLCGYRTQLDGQ 70
            ||.:.|:|.:|...|.     .|..|.|.||||..|:.:..|..   ..:..|.:|  |.|
Frog     5 ELTNDLTCSVCQEIYK-----EPVTLPCGHSFCIPCIGKTWDEQHRIEEDASCPVC--RKQ---- 58

  Fly    71 QLPQSVTIMYLLRELPALILGRAMLDFSYKRSSTIEMSIEEAPSSPSKNWVEDINVESFLATSAE 135
                                        |||...:..:|      ...|..|.|..|:      .
Frog    59 ----------------------------YKRKPELNRNI------ALHNIAEQILPEN------T 83

  Fly   136 HCFIHAMPNSTWCHNCQRLLCRACSDVPLHQDHILVRQVDYHDLISQLLNSELRKIKSTAVHAKE 200
            .|..|.......|.:...|:|.:|..|..|:.|    ||:..|...:....:||::.......||
Frog    84 KCSAHNKHLKYHCSDDGALICESCCHVGDHKGH----QVESLDKAFEKQKEKLREVWKKLTPEKE 144

  Fly   201 LATHEMDLLRE--------LCEACYRVQLHVK--REMLEHHSSMVAASMIGWHRLAERDLHRVGR 255
            ....::..|:|        |.....||....|  :||||              .|.::.|..:..
Frog   145 KTEGQVQRLQENRKKVEEILAGETERVTTLFKEIKEMLE--------------ALEKKSLDEISE 195

  Fly   256 LTGAKML---QVLAHLATQRQRYERQLDQVHFQCRM 288
            |....:|   .::..|.|::.....::..:...|.|
Frog   196 LLKRHLLPFTDLIQQLETKKGELSMKICNIKNLCNM 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5071	NP_001303432.1	RING	16..59	CDD:238093	12/45 (27%)
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131
LOC100489639	XP_002939598.3	RING_Ubox	10..56	CDD:418438	15/52 (29%)
		Bbox2_TRIM16-like	84..129	CDD:380827	12/48 (25%)
		BBC	128..248	CDD:128778	22/118 (19%)
		SPRY_PRY_C-I_2	299..464	CDD:293949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	44	1.000	Inparanoid score	I5302
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960