Protein Alignment msi and ZCRB1

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_149105.3
• Gene: ZCRB1 / 85437
• HGNCID: 29620
• Length: 217
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 52/223 - (23%)
• Similarity: 83/223 - (37%)
• Gaps: 74/223 - (33%)

  Fly   192 LSGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITF----- 251
            :|||..  |:...::|..|.:..:::.|...|:.:|.|..|.||||..|::|:|..||.|
Human     1 MSGGLA--PSKSTVYVSNLPFSLTNNDLYRIFSKYGKVVKVTIMKDKDTRKSKGVAFILFLDKDS 63

  Fly   252 QEPCT--------VEKVLKVPIHTLDGKKID---------------------PKHATPKNR---- 283
            .:.||        ..:|:|..|...:|:..:                     ..:|.|||.
Human    64 AQNCTRAINNKQLFGRVIKASIAIDNGRAAEFIRRRNYFDKSKCYECGESGHLSYACPKNMLGER 128

  Fly   284 --PRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENED-VV 345
              |::..|.||         ..|.|         |.||...:.:.:.           |.|| .:
Human   129 EPPKKKEKKKK---------KKAPE---------PEEEIEEVEESED-----------EGEDPAL 164

  Fly   346 DRVCE-IHFHTIKNKKVECKKAQPKEAV 372
            |.:.: |.|...|.:: |.||.:|...|
Human   165 DSLSQAIAFQQAKIEE-EQKKWKPSSGV 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	23/107 (21%)
		RRM2_MSI	292..365	CDD:240769	14/74 (19%)
ZCRB1	NP_149105.3	RRM_ZCRB1	9..84	CDD:409827	21/74 (28%)
		PTZ00368	<97..123	CDD:173561	2/25 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..217		24/102 (24%)