DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msi and AT2G33410

DIOPT Version :9

Sequence 1:	NP_001247303.1	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_180899.1	Gene:	AT2G33410 / 817905	AraportID:	AT2G33410	Length:	404	Species:	Arabidopsis thaliana

Alignment Length:	460	Identity:	133/460 - (28%)
Similarity:	195/460 - (42%)	Gaps:	102/460 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 GKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHT 267
            ||||:||:||.|..:.|:|||:.||.|..|.:|::..|.|.|||||:.|.:|..:::||: ..|.
plant     6 GKLFIGGISWDTDENLLREYFSNFGEVLQVTVMREKATGRPRGFGFVAFSDPAVIDRVLQ-DKHH 69

  Fly   268 LDGKKIDPKHA------TPKNRPRQAN-----------KTKKIFVGGVSQDTSAEEVKAYFSQFG 315
            :|.:.:|.|.|      :|..|....|           :||||||||:....:::|.:|||..:|
plant    70 IDNRDVDVKRAMSREEQSPAGRSGTFNASRNFDSGANVRTKKIFVGGLPPALTSDEFRAYFETYG 134

  Fly   316 PVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQ 380
            ||.:.|:::||.|:|.||||||:|::||.||.|....||.:..|:||.|:|.||:| .|
plant   135 PVSDAVIMIDQTTQRPRGFGFVSFDSEDSVDLVLHKTFHDLNGKQVEVKRALPKDA-NP------ 192

  Fly   381 KRIMLGTLGVQLPTAPGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAAQQAALISQNPFQV 445
                    |:    |.|   |.||:|.|...|           ....:..:..:..:.|....|.
plant   193 --------GI----ASG---GGRGSGGAGGFP-----------GYGGSGGSGYEGRVDSNRYMQP 231

  Fly   446 QNAAAAASIANQAGFGKLLTTYPQTALHSVRY---APYSIPASAATANAALMQAHQAQSVAAAAH 507
            ||..:.......:|:|   |.|...: :.|.|   ..|..||.|...|         .||..|..
plant   232 QNTGSGYPPYGGSGYG---TGYGYGS-NGVGYGGFGGYGNPAGAPYGN---------PSVPGAGF 283

  Fly   508 HHQQQQQQQHHHQQQTHNAHVAAAQQQQQSHHNAVSNPASQAHSAAAAAAL--AANAANGAGAAG 570
            ....:...              .||......:....|.|....|....:|:  .|.|:.|.|:.|
plant   284 GSGPRSSW--------------GAQAPSGYGNVGYGNAAPWGGSGGPGSAVMGQAGASAGYGSQG 334

  Fly   571 --------AHSLAAAAQQAGLMAGN-PLNAAAAAAAAAANPAAAYSNYALANVDMSSFQGVDWST 626
                    ::...:|....|..:|| |.|......|.|.:.:..|.|:          ||.:...
plant   335 YGYGGNDSSYGTPSAYGAVGGRSGNMPNNHGGGGYADALDGSGGYGNH----------QGNNGQA 389

  Fly   627 MYGMG 631
            .||.|
plant   390 GYGGG 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	30/70 (43%)
msi	NP_001247303.1	RRM2_MSI	292..365	CDD:240769	35/72 (49%)
AT2G33410	NP_180899.1	RRM_SF	8..78	CDD:418427	30/70 (43%)
AT2G33410	NP_180899.1	RRM2_Hrp1p	111..188	CDD:409767	37/76 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	1.000	Domainoid score	I2908
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	1	1.000	-	-		mtm1160
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X310
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.770