Protein Alignment msi and Celf3

DIOPT Version :9

• Sequence 1: NP_001247303.1
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001276542.1
• Gene: Celf3 / 78784
• MGIID: 1926034
• Length: 494
• Species: Mus musculus
• Alignment Length: 489
• Identity: 113/489 - (23%)
• Similarity: 169/489 - (34%)
• Gaps: 141/489 - (28%)

  Fly   199 DPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKV 263
            :|...|||||.:........||..|..||.:.::.::||..|...:|..|:|:   |..:..||.
Mouse     3 EPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTY---CARDSALKA 64

  Fly   264 --PIH---TLDG--KKIDPKHATPKNRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETV 321
              .:|   ||.|  :.|..|.|..::|    .:.:|:|||.:.:..:.|:|:..|..||.::|..
Mouse    65 QSALHEQKTLPGMNRPIQVKPADSESR----GEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECT 125

  Fly   322 MLM--DQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIM 384
            :|.  |..:|   |..||.|:........... .|:.:...........|.|.|...:.|::...
Mouse   126 VLRGPDGTSK---GCAFVKFQTHAEAQAAINT-LHSSRTLPGASSSLVVKFADTEKERGLRRMQQ 186

  Fly   385 LGT-LGVQLPTA----------------PGQLIGARGAGVATMNPLAMLQ--------------- 417
            :.| ||:..|.|                ...|:.|..|.::.|..:|.:|
Mouse   187 VATQLGMFSPIALQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAISANGLIAT 251

  Fly   418 --NPTQLLQSPAAAAAAQQAAL---ISQNPFQVQNAAAAASIANQAGFGKLLTTYPQTALHSVRY 477
              .|:....:|.|.||...:|:   :..|.:...........|..|.:...:..||..||.:.|.
Mouse   252 PITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPDEALSAERS 316

  Fly   478 A----------PYSIPASAATANAA----LMQAH-----------QAQSVAAAA----------- 506
            |          .:.:..|||.:.||    |.||:           .|.|:.|.|
Mouse   317 AGGVPIMSQAHSWLVMLSAAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQ 381

  Fly   507 -----HHHQQQQQQQHHHQQQTHN---------------------------AHVAAAQ------Q 533
                 ...|||||||...|||...                           .||.:|:      .
Mouse   382 PPPPPQQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRAT 446

  Fly   534 QQQSHHNAVS--NPASQAHSAAAAAALAANAANG 565
            .|......||  ||||        |..|..|.||
Mouse   447 NQSKCFGFVSFDNPAS--------AQAAIQAMNG 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	23/77 (30%)
		RRM2_MSI	292..365	CDD:240769	18/74 (24%)
Celf3	NP_001276542.1	RRM1_CELF3_4_5_6	2..88	CDD:410041	27/87 (31%)
		RRM2_CELF3_4_5_6	94..174	CDD:410043	19/83 (23%)
		PRK12323	<214..379	CDD:237057	33/164 (20%)
		RRM3_CELF3_4_5_6	405..483	CDD:241083	15/76 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900