Protein Alignment msi and Msi2

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: XP_006534494.1
• Gene: Msi2 / 76626
• MGIID: 1923876
• Length: 378
• Species: Mus musculus
• Alignment Length: 455
• Identity: 165/455 - (36%)
• Similarity: 214/455 - (47%)
• Gaps: 148/455 - (32%)

  Fly   182 SGSSGRSTPSLSGGSGSDPA--PGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSR 244
            :||.|.|      ||.:|..  |||:|:||||||||.|.|::||:.||.:.:.::|:||.|:|||
Mouse     4 NGSPGTS------GSANDSQHDPGKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSR 62

  Fly   245 GFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPKN-RPR----------------------- 285
            ||||:||.:|.:|:|||..|.|.||.|.||||.|.|:. :|:
Mouse    63 GFGFVTFADPASVDKVLGQPHHELDSKTIDPKVAFPRRAQPKSQEQGGSWKRTWTTVQARAASGD 127

  Fly   286 -QANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVC 349
             ...:||||||||:|.:|..|:||.||.|||.||:.:::.|:.|.||||||||||||||||::||
Mouse   128 QMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGFGFVTFENEDVVEKVC 192

  Fly   350 EIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPTAPGQLIGARGAGV---ATMN 411
            |||||.|.||.||||||||||.:.|                     ||....|||...   |.|.
Mouse   193 EIHFHEINNKMVECKKAQPKEVMFP---------------------PGTRGRARGLPYTMDAFML 236

  Fly   412 PLAMLQNPTQLLQSPAAAAAAQQAALISQNPFQVQNAAAAASIANQAGFGKLLTTYPQTALHSVR 476
            .:.||..|..:                                   |.:|:   .||       .
Mouse   237 GMGMLGYPNFV-----------------------------------ATYGR---GYP-------G 256

  Fly   477 YAP---YSIPASAATANAALMQAHQAQSVAAAAHHHQQQQQQQHHHQQQTHNAHVAAAQQQQQSH 538
            :||   |..||.....||:...|... .|||||                     ||||:....:.
Mouse   257 FAPSYGYQFPALLPYLNASFPAAAYG-PVAAAA---------------------VAAARGSVLNS 299

  Fly   539 HNAVSN---PASQAHSAAAAAALAANAANGAGAAGAHS-------LAAAAQQAGLMAGNPLNAAA 593
            ::|..|   |||.|.|         |.|...|..||:|       ...|:|.:|:  ||.::||:
Mouse   300 YSAQPNFGAPASPAGS---------NPARPGGFPGANSPGPVADLYGPASQDSGV--GNYISAAS 353

  Fly   594  593
            Mouse   354  353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	43/73 (59%)
		RRM2_MSI	292..365	CDD:240769	49/72 (68%)
Msi2	XP_006534494.1	RRM_SF	17..104	CDD:473069	47/86 (55%)
		PABP-1234	<35..363	CDD:130689	146/418 (35%)
		RRM2_MSI	135..208	CDD:240769	49/72 (68%)