DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msi and hnrnpa3

DIOPT Version :9

Sequence 1:	NP_001247303.1	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001315077.1	Gene:	hnrnpa3 / 751729	ZFINID:	ZDB-GENE-060224-1	Length:	340	Species:	Danio rerio

Alignment Length:	170	Identity:	66/170 - (38%)
Similarity:	107/170 - (62%)	Gaps:	3/170 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 KLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTL 268
            |||:||||::|:.|.|:.:|..:|.:||.::|:||..:|||||||:|:.....|:..:....|.:
Zfish    14 KLFIGGLSFETTEDSLRAHFEQWGKLTDCVVMRDPANKRSRGFGFVTYSSVSEVDAAMTARPHKV 78

  Fly   269 DGKKIDPKHATPK---NRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKR 330
            ||:.::||.|..:   |:|......|||||||:.:||....::.||..:|.:|...::.::.|.:
Zfish    79 DGRVVEPKRAVSREDSNKPGAHLTVKKIFVGGIKEDTEEYHIREYFECYGKIETIDIMEERSTGK 143

  Fly   331 HRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKE 370
            .|||.||||::.|.||::....:|||.:...|.:||.||:
Zfish   144 KRGFCFVTFDDHDTVDKIVAQKYHTINSHNCEVRKALPKQ 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	28/70 (40%)
msi	NP_001247303.1	RRM2_MSI	292..365	CDD:240769	27/72 (38%)
hnrnpa3	NP_001315077.1	RRM1_hnRNPA_like	14..91	CDD:241022	32/76 (42%)
		RRM2_hnRNPA3	104..183	CDD:241026	31/78 (40%)
		HnRNPA1	<296..>315	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910