DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment msi and hnrnpab

DIOPT Version :9

Sequence 1:	NP_001247303.1	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	XP_012814656.1	Gene:	hnrnpab / 734098	XenbaseID:	XB-GENE-6042555	Length:	326	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	87/213 - (40%)
Similarity:	121/213 - (56%)	Gaps:	9/213 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 ENVNASAGAGQNNGQAAMGGSNKSGSSGRSTPSLSGGSGSDPAPG-KLFVGGLSWQTSSDKLKEY 222
            |...:....|||..:.....::|........|.:|    |....| |:|||||||.||...||:|
Frog    24 EAAESKVPGGQNGAEGDQINASKGEEDAGCVPDIS----SPLTEGVKMFVGGLSWDTSKKDLKDY 84

  Fly   223 FNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPKNRPRQA 287
            |:.||.|:|..|..||.|.||||||||.|::..:|:|||:...|.|||:.||||.|....:
Frog    85 FSKFGEVSDCTIKMDPNTGRSRGFGFILFKDAASVDKVLEQKEHRLDGRLIDPKKAMAMKK---- 145

  Fly   288 NKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIH 352
            :..|||||||::.:...::::.||..||.:|...:.||.:|.:.|||.|:||:.|:.|.::.|..
Frog   146 DPIKKIFVGGLNPEAGEDKIREYFETFGEIEAIELPMDPKTNKRRGFVFITFKEEEPVKKILEKK 210

  Fly   353 FHTIKNKKVECKKAQPKE 370
            ||.:...|.|.|.|||||
Frog   211 FHNVSGSKCEIKIAQPKE 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	40/70 (57%)
msi	NP_001247303.1	RRM2_MSI	292..365	CDD:240769	27/72 (38%)
hnrnpab	XP_012814656.1	CBFNT	1..52	CDD:311868	5/27 (19%)
		RRM1_hnRNPAB	66..140	CDD:241201	43/73 (59%)
		RRM2_hnRNPAB	145..224	CDD:241028	29/82 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D496221at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920