Protein Alignment msi and Rbm4b

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_079993.2
• Gene: Rbm4b / 66704
• MGIID: 1913954
• Length: 357
• Species: Mus musculus
• Alignment Length: 433
• Identity: 94/433 - (21%)
• Similarity: 158/433 - (36%)
• Gaps: 104/433 - (24%)

  Fly   204 KLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTL 268
            |||:|.|..:.:..:::..|..:|.|.:..|:|:        :||:..::....|..    |..|
Mouse     3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDA----IRNL 55

  Fly   269 DGKKIDPKHATPKNRPRQANKTK---KIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKR 330
            ...|:   |....|.....||:|   |:.||.:|...:.:|::|.|.::|||.|..::.|
Mouse    56 HHYKL---HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD----- 112

  Fly   331 HRGFGFVTFEN-EDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPT 394
               :.||..|. ||.|:.:     ..:.|.:.:.|:               ..:.|.|  .:|.|
Mouse   113 ---YAFVHMERAEDAVEAI-----RGLDNTEFQGKR---------------MHVQLST--SRLRT 152

  Fly   395 APGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAAQQAALISQNPFQVQNAAAAASIANQAG 459
            |||                        :..........::.....:.|  |......|....|..
Mouse   153 APG------------------------MGDQSGCYRCGKEGHWSKECP--VDRTGRVADFTEQYN 191

  Fly   460 --FGKLLTTYPQTALHSVRYAPYSIPASAATANAAL-------MQAHQAQSVAAAAHHHQQQQQQ 515
              :|.:.|.|......|:.|         ..|..||       :::::|.:.||||..:...:|.
Mouse   192 EQYGAVRTPYTMGYGESMYY---------NDAYGALDYYKRYRVRSYEAVAAAAAASAYNYAEQT 247

  Fly   516 QHHHQQQTHNA---HVAAAQQQQQSHHNAVSNPASQAHSAAAAAALAANAANGAGAAGAHSLAAA 577
            ..|..|...:|   |:.:........| .:.|..|.|.|||.||| |:::..|...:.....||.
Mouse   248 MSHLPQVQSSAVPSHLNSTSVDPYDRH-LLQNSGSAATSAAMAAA-ASSSYYGRDRSPLRRNAAV 310

  Fly   578 AQQAGLMAG-NPLNAAAAAAAAAANPAAAYSNYALANVDMSSF 619
            ....|...| .|.:..:.|:||..|     |.|.:|..:...:
Mouse   311 LPAVGEGYGYGPESEMSQASAATRN-----SLYDMARYEREQY 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	16/73 (22%)
		RRM2_MSI	292..365	CDD:240769	19/73 (26%)
Rbm4b	NP_079993.2	RRM1_RBM4	2..68	CDD:410018	18/79 (23%)
		RRM2_RBM4	78..144	CDD:410019	20/93 (22%)
		PTZ00368	<145..>181	CDD:173561	9/63 (14%)
		ZnF_C2HC	161..176	CDD:197667	0/14 (0%)
		Interaction with TNPO3. /evidence=ECO:0000250	196..357		41/169 (24%)