DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msi and hnrnpd

DIOPT Version :9

Sequence 1:	NP_001247303.1	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001103930.1	Gene:	hnrnpd / 560522	ZFINID:	ZDB-GENE-070424-97	Length:	314	Species:	Danio rerio

Alignment Length:	207	Identity:	90/207 - (43%)
Similarity:	121/207 - (58%)	Gaps:	13/207 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 GQNNGQAAMGGSNKSGSSGRSTPSLSGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDV 232
            |:..|:..|.|.|  |..|.:..|....|.::...||:|||||||.|:...||:||..||.|.|.
Zfish    21 GEGFGEEQMSGDN--GGQGEAEGSKIDASKNEEDEGKMFVGGLSWDTTKKDLKDYFTKFGEVVDC 83

  Fly   233 LIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPKNRPRQANKT----KKI 293
            .:..||:|.|||||||:.|:|..:||||:....|.|:||.||||.|       :|.||    |||
Zfish    84 TLKLDPLTGRSRGFGFVLFKEAESVEKVITQKEHKLNGKVIDPKKA-------KAMKTKEPVKKI 141

  Fly   294 FVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKN 358
            ||||:|.||..|:::.||..:|.||...:.|:.:|.:.|||.|:||:.|:.|.::.|..:|.|..
Zfish   142 FVGGLSPDTPEEKIREYFDAYGEVESIELPMENKTNKRRGFCFITFKEEEPVKKIMEKMYHNIGL 206

  Fly   359 KKVECKKAQPKE 370
            .|.|.|.|..||
Zfish   207 SKCEVKVAMSKE 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	38/70 (54%)
msi	NP_001247303.1	RRM2_MSI	292..365	CDD:240769	30/72 (42%)
hnrnpd	NP_001103930.1	CBFNT	3..54	CDD:285369	9/34 (26%)
		RRM1_hnRNPD_like	56..129	CDD:241019	40/72 (56%)
		RRM2_hnRNPD	140..214	CDD:241027	31/73 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D496221at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920