Protein Alignment msi and RBM38

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001278709.1
• Gene: RBM38 / 55544
• HGNCID: 15818
• Length: 271
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 78/330 - (23%)
• Similarity: 121/330 - (36%)
• Gaps: 99/330 - (30%)

  Fly   188 STPSLSGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGF-ITF 251
            :.|....||..|....|:|||||.:.|:...|::||..||.:.:.:::.|..|.:|||:|| |.|
Human    19 AAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFGIIF 83

  Fly   252 QEPCTVEKVLKVPIHTLDGKKIDPKHATPKNRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGP 316
            .....:.:.|     ..||:..:|               ..||||
Human    84 VLEGHISQAL-----NFDGRSWNP---------------GGIFVG-------------------- 108

  Fly   317 VEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECK----KAQPKEAVTPAA- 376
                    :.|         ||..:....:|.|:.....|..:|....    .|:|:...|..|
Human   109 --------EPQ---------VTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAI 156

  Fly   377 --QLLQKRIMLGTLGVQ----LPTA---PGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAA 432
              |.|...::..|.|:.    .|.|   |..:|.|.        |:..|.:| .:..:||:.|.|
Human   157 GVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPAA--------PVPSLSSP-YIEYTPASPAYA 212

  Fly   433 Q-QAALISQNPFQVQNAAAAASIANQAGFGKLLTTYPQTALHSVRYAPYSIPASAATANAALM-Q 495
            | ..|...|.|:    ||:.|:.|:..|:     :||..       .|.::.|:|......:. |
Human   213 QYPPATYDQYPY----AASPATAASFVGY-----SYPAA-------VPQALSAAAPAGTTFVQYQ 261

  Fly   496 AHQAQ 500
            |.|.|
Human   262 APQLQ 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	25/74 (34%)
		RRM2_MSI	292..365	CDD:240769	11/76 (14%)
RBM38	NP_001278709.1	RRM_RBM24_RBM38_like	34..141	CDD:409818	36/163 (22%)
		PABP-1234	<46..269	CDD:130689	67/303 (22%)