Protein Alignment msi and TRNAU1AP

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_060316.1
• Gene: TRNAU1AP / 54952
• HGNCID: 30813
• Length: 287
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 71/337 - (21%)
• Similarity: 116/337 - (34%)
• Gaps: 86/337 - (25%)

  Fly   205 LFVGGLSWQTSSDKLKEYFNMFG-TVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTL 268
            |::|.|......:.:...|...| ||..|.|:::.:|....|:.|:.|.:..|.||.|    |.:
Human     5 LWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCL----HKI 65

  Fly   269 DGKKIDPKHATPKNR--------PRQANKTKK--IFVGGVSQDTSAEEVKAYFSQFGPVEETVML 323
            :||.:  ..|||..|        .:|.:.:.:  :|||.::.|.....:..:|.:..|......:
Human    66 NGKPL--PGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKV 128

  Fly   324 MDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTL 388
            :..||...:|:|||.|.:|                       .:.|.|:|..    |..:.||:.
Human   129 VLDQTGVSKGYGFVKFTDE-----------------------LEQKRALTEC----QGAVGLGSK 166

  Fly   389 GVQLPTAPGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAAQQAALISQNPF--QVQNAAAA 451
            .|:|..|               .|.|....|.:.          .|....|.|.:  |.||..|
Human   167 PVRLSVA---------------IPKASRVKPVEY----------SQMYSYSYNQYYQQYQNYYA- 205

  Fly   452 ASIANQAGF----GKLLTTYPQTALHSVRYAPYSIPASAATANAALMQAHQAQSVAAAAHHHQQQ 512
                 |.|:    |....:|||..     |...::.......:.||........|..|.....:|
Human   206 -----QWGYDQNTGSYSYSYPQYG-----YTQSTMQTYEEVGDDALEDPMPQLDVTEANKEFMEQ 260

  Fly   513 QQQQHHHQQQTH 524
            .::.:......|
Human   261 SEELYDALMDCH 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	20/73 (27%)
		RRM2_MSI	292..365	CDD:240769	14/74 (19%)
TRNAU1AP	NP_060316.1	RRM1_SECp43	4..87	CDD:410022	24/87 (28%)
		RRM2_SECp43	95..176	CDD:410024	23/122 (19%)
		Trnau1ap	<206..284	CDD:465438	13/72 (18%)