Protein Alignment msi and Hnrnpa2b1

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001361674.1
• Gene: Hnrnpa2b1 / 53379
• MGIID: 104819
• Length: 353
• Species: Mus musculus
• Alignment Length: 170
• Identity: 63/170 - (37%)
• Similarity: 109/170 - (64%)
• Gaps: 3/170 - (1%)

  Fly   204 KLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTL 268
            |||:||||::|:.:.|:.|:..:|.:||.::|:||.::|||||||:||.....|:..:....|::
Mouse    22 KLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSI 86

  Fly   269 DGKKIDPKHATPK---NRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKR 330
            ||:.::||.|..:   .:|......||:||||:.:||....::.||.::|.::...::.|:|:.:
Mouse    87 DGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGK 151

  Fly   331 HRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKE 370
            .||||||||::.|.||::....:|||.....|.:||..::
Mouse   152 KRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQ 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	31/73 (42%)
		RRM2_MSI	292..365	CDD:240769	27/72 (38%)
Hnrnpa2b1	NP_001361674.1	Nuclear localization signal. /evidence=ECO:0000255	9..15
		RRM1_hnRNPA2B1	19..99	CDD:410155	32/76 (42%)
		RRM2_hnRNPA2B1	112..191	CDD:409995	30/78 (38%)
		Disordered. /evidence=ECO:0000250|UniProtKB:P22626	193..353
		HnRNPA1	302..326	CDD:463312
		Nuclear targeting sequence. /evidence=ECO:0000250	308..347