DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msi and hnrnpdl

DIOPT Version :9

Sequence 1:	NP_001247303.1	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001011015.1	Gene:	hnrnpdl / 496424	XenbaseID:	XB-GENE-495016	Length:	297	Species:	Xenopus tropicalis

Alignment Length:	227	Identity:	100/227 - (44%)
Similarity:	126/227 - (55%)	Gaps:	23/227 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 STPSLSGGSGSDPA-----PGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFG 247
            :||..:.||..:.:     .||:|:|||||.||...|.||.:.||.|.|..|..||||.||||||
Frog     6 ATPDFNEGSKINASKNQQDEGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFG 70

  Fly   248 FITFQEPCTVEKVLKVPIHTLDGKKIDPKHATP---KNRPRQANKTKKIFVGGVSQDTSAEEVKA 309
            |:.|::..:|:|||:...|.||||.||||.|..   |..|      ||:||||:|.:|:.|::|.
Frog    71 FVLFKDAVSVDKVLETKEHKLDGKLIDPKRAKALKGKEPP------KKVFVGGLSPETTEEQIKQ 129

  Fly   310 YFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTP 374
            ||..||.:|...:.||.:|...|||.|||:..|:.|.::.|..||.|...|.|.|.|||||....
Frog   130 YFGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLESRFHQIGTGKCEIKVAQPKEVYRQ 194

  Fly   375 AAQLLQKRIMLGTLGVQLPTAPGQLIGARGAG 406
            ..|..||    |..|.  .|..|   ||||.|
Frog   195 QQQKQQK----GGRGA--ATGRG---GARGRG 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	39/70 (56%)
msi	NP_001247303.1	RRM2_MSI	292..365	CDD:240769	31/72 (43%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		4/14 (29%)
		RRM1_hnRPDL	27..102	CDD:410152	42/74 (57%)
		RRM2_hnRPDL	112..186	CDD:409998	32/73 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	192..224		12/35 (34%)
		Trnau1ap	222..>278	CDD:407550
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D496221at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920