Protein Alignment msi and MSI1

DIOPT Version :9

• Sequence 1: NP_001247303.1
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_002433.1
• Gene: MSI1 / 4440
• HGNCID: 7330
• Length: 362
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 134/312 - (42%)
• Similarity: 180/312 - (57%)
• Gaps: 39/312 - (12%)

  Fly   190 PSL-SGGSGSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQE 253
            |.| |..|..||.  |:|:|||||||:.:.|:|||..||.|.:.|:|:||:|:|||||||:||.:
Human     8 PGLASPDSPHDPC--KMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMD 70

  Fly   254 PCTVEKVLKVPIHTLDGKKIDPKHATPKN-RPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPV 317
            ...|:|||....|.||.|.||||.|.|:. :|:...:||||||||:|.:|:.|:||.||.|||.|
Human    71 QAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKV 135

  Fly   318 EETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLL-QK 381
            ::.:::.|:.|.|||||||||||:||:|::|||||||.|.||.||||||||||.::|..... :.
Human   136 DDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRS 200

  Fly   382 RI-------------MLGTLGVQLPTAPGQLIGARGAGVATMNPLAMLQNPTQLLQSPA------ 427
            |:             |||..|.|..|...:.......|.....|...::. |.|..:|.
Human   201 RVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVER-TPLPSAPVLPELTA 264

  Fly   428 --------AAAAAQQAALI---SQNPFQVQNAAAAASIANQAGFGKLLTTYP 468
                    .||||..||::   ..:|:.:  |....|..::.| |.|.||.|
Human   265 IPLTAYGPMAAAAAAAAVVRGTGSHPWTM--APPPGSTPSRTG-GFLGTTSP 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	39/70 (56%)
		RRM2_MSI	292..365	CDD:240769	46/72 (64%)
MSI1	NP_002433.1	RRM1_MSI	21..96	CDD:409990	42/74 (57%)
		PABP-1234	<32..339	CDD:130689	119/286 (42%)
		RRM2_MSI	110..183	CDD:240769	46/72 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4205
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000417
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101082
Panther	1	1.100	-	-	O	PTHR48032
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X310
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.810