Protein Alignment msi and trv

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001163754.3
• Gene: trv / 43362
• FlyBaseID: FBgn0085391
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 618
• Identity: 148/618 - (23%)
• Similarity: 221/618 - (35%)
• Gaps: 194/618 - (31%)

  Fly     6 PAVAAKLPFPYNVPPPLQAAAAAAAAVPNL--RFQTPIKAFAC-LTAATRSVSEMNATSLYAGNP 67
            |.:.||...|...|||:.....|....|.|  ....|.::|.| |.:.|.:...:..|  |....
  Fly   170 PLLHAKSVPPPPQPPPMLTHFQAMMQPPPLPPSPMMPPQSFGCPLPSRTPATPPLPGT--YRVQS 232

  Fly    68 MENAAAAAAAAAAGLIDPHHNRDLHQALVASIANNSVAAIGGGLTTAAVLKSAAQQSQQAVQQNQ 132
            :::|||||.:|.      ..|..|.:.|                       .|.:..:.|::.|.
  Fly   233 LKSAAAAAVSAY------QRNGKLPRNL-----------------------PALRAMEMALRTNS 268

  Fly   133 NAVVVTPGLEQPKQEPAQQAALALLKENVNASAGAGQNNGQAAMGGSNKSGSSGRSTPSLSGGSG 197
            .|   ||        ||.. :|.|...:...:.|.||:        ...|.......|.|.
  Fly   269 FA---TP--------PAPH-SLPLPPPHAARTEGGGQD--------MEDSDEEMEYMPPLH---- 309

  Fly   198 SDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLK 262
               ....:|||.||.:..:.:|:|.|..||.::|..:::||.|.:|:|:||::|.:....|..
  Fly   310 ---KQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESA-- 369

  Fly   263 VPIHTLDG-----KKIDPKHATPK-----------------NRPRQANKTKKIFVGGVSQDTSA- 304
              |..::|     :.|....||.|                 |:...:|.|  ::||||:...:|
  Fly   370 --ITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCT--VYVGGVNSALTAL 430

  Fly   305 -EEV-KAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDR-VCEIHFHTIKNKKVEC--- 363
             ||| :..|:.:|.::|..:..|      :|:.||.|..::.... :..:|...|..:.|:|
  Fly   431 SEEVLQKTFAPYGAIQEIRVFKD------KGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWG 489

  Fly   364 -KKAQPKEAVTPAAQLLQKRIMLGTLGVQLPTAPGQLIGARGAGVATMNPLAMLQNPTQLLQSPA 427
             :...|..|.|.|                                            ||.|.|.|
  Fly   490 KESGDPNNAQTIA--------------------------------------------TQALNSAA 510

  Fly   428 AAAAAQQAALISQNPFQVQNAAAAASIANQAGFGKLLTTYPQTALHSVRYAPY-SIPASAATANA 491
            ||||.        .|:.|..|||||:      :|:      |.|.....|:|. :.|||:||| |
  Fly   511 AAAAG--------FPYGVGAAAAAAA------YGQ------QLAATGCWYSPTPTYPASSATA-A 554

  Fly   492 ALMQAHQAQSVAAAAHHHQQQQQQQHHHQ----QQTHNAHVAAAQQQQQSHHNAVSNPASQAHSA 552
            |:..|  |.|.||..:...|..|..|..|    ||.:...........|....|..:||.|.
  Fly   555 AVTPA--AASAAAVQNQFLQGIQGYHFGQYGGYQQGYMGMGVQIPATWQGVTQAQISPAQQL--- 614

  Fly   553 AAAAALAANAANGAGAAGAHSLAAAAQQAGLMA 585
                        ..|.||    .|..|.||::|
  Fly   615 ------------ATGVAG----TAIPQAAGVVA 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	23/78 (29%)
		RRM2_MSI	292..365	CDD:240769	20/80 (25%)
trv	NP_001163754.3	RRM2_TIA1_like	313..387	CDD:409789	23/77 (30%)
		RRM3_TIA1_like	416..489	CDD:409790	21/80 (26%)