DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment msi and hnrnpa0a

DIOPT Version :9

Sequence 1:	NP_001247303.1	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_997810.2	Gene:	hnrnpa0a / 323529	ZFINID:	ZDB-GENE-030131-2249	Length:	305	Species:	Danio rerio

Alignment Length:	206	Identity:	72/206 - (34%)
Similarity:	109/206 - (52%)	Gaps:	28/206 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   204 KLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTL 268
            |||||||:.||:.|.|:.:|..:|.:||.:::::...:|||.|||:|:..|...:..:....|.|
Zfish    11 KLFVGGLNVQTTDDGLRNHFEQYGKLTDCVVVQNQQLKRSRCFGFVTYSSPDEADSAMSARPHIL 75

  Fly   269 DGKKIDPKHATPK---NRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKR 330
            ||..::.|.|..:   .:|....|.||||:||:..|...:.::..|||||.||:..::.|::|.:
Zfish    76 DGNNVELKRAVAREDAGKPEALAKVKKIFIGGLKDDIEEDHLRDCFSQFGAVEKAEVITDKETGK 140

  Fly   331 HRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPTA 395
            .||||||.||:.|..|:...:.||.|...|||.|||..|:.:
Zfish   141 KRGFGFVYFEDNDSADKAVVLKFHIINGHKVEVKKALTKQEM----------------------- 182

  Fly   396 PGQLIGARGAG 406
              |..|:||.|
Zfish   183 --QAAGSRGGG 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_001247303.1	RRM1_hnRNPA_hnRNPD_like	205..276	CDD:240771	26/70 (37%)
msi	NP_001247303.1	RRM2_MSI	292..365	CDD:240769	31/72 (43%)
hnrnpa0a	NP_997810.2	RRM1_hnRNPA0	8..86	CDD:240772	28/74 (38%)
		RRM_SF	102..181	CDD:302621	35/78 (45%)
		HnRNPA1	260..286	CDD:288479
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910