Protein Alignment msi and HNRNPD

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_112738.1
• Gene: HNRNPD / 3184
• HGNCID: 5036
• Length: 355
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 100/279 - (35%)
• Similarity: 141/279 - (50%)
• Gaps: 43/279 - (15%)

  Fly   150 QQAALALLKENVNASAGAGQNNGQAAMGGSNKSGSS------------------GRSTPSLSGGS 196
            |:.|:....:...|:||:|...|.....|..:.||:                  ..|:|..|..:
Human    26 QEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAA 90

  Fly   197 GSDPAPGKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVL 261
            .:.....|:|:|||||.|:...||:||:.||.|.|..:..||:|.|||||||:.|:|..:|:||:
Human    91 TAQREEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVM 155

  Fly   262 KVPIHTLDGKKIDPKHATPKNRPRQANKT----KKIFVGGVSQDTSAEEVKAYFSQFGPVEETVM 322
            ....|.|:||.||||.|       :|.||    |||||||:|.||..|:::.||..||.||...:
Human   156 DQKEHKLNGKVIDPKRA-------KAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIEL 213

  Fly   323 LMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGT 387
            .||.:|.:.|||.|:||:.|:.|.::.|..:|.:...|.|.|.|..||.       .|::...|:
Human   214 PMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQ-------YQQQQQWGS 271

  Fly   388 LGVQLPTAPGQLIGARGAG 406
            .|       |....|||.|
Human   272 RG-------GFAGRARGRG 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	39/73 (53%)
		RRM2_MSI	292..365	CDD:240769	31/72 (43%)
HNRNPD	NP_112738.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		13/65 (20%)
		CBFNT	<60..78	CDD:311868	1/17 (6%)
		RRM1_hnRNPD	99..172	CDD:410150	38/72 (53%)
		RRM2_hnRNPD	183..257	CDD:241027	32/73 (44%)