back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment msi and RBM24

DIOPT Version :10

Sequence 1:	NP_733108.2	Gene:	msi / 43087	FlyBaseID:	FBgn0011666	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001137414.1	Gene:	RBM24 / 221662	HGNCID:	21539	Length:	236	Species:	Homo sapiens

Alignment Length:	337	Identity:	96/337 - (28%)
Similarity:	124/337 - (36%)	Gaps:	117/337 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   277 HATPKNRPRQANKTKKIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFEN 341
            |.|.|:     ....||||||:...|:...::.||..||.:||.|::.|:||.:.||:||||..:
Human     2 HTTQKD-----TTYTKIFVGGLPYHTTDASLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMAD 61

  Fly   342 EDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPTAPGQLIGARGAG 406
            ....:|.|:     ..|..::.:||....|...|    :.|||          .||...     |
Human    62 RAAAERACK-----DPNPIIDGRKANVNLAYLGA----KPRIM----------QPGFAF-----G 102

  Fly   407 VATMNPLAMLQNPTQLLQSPA----AAAAAQQAALISQNPFQVQNAAAAASIANQAGFGKLLTTY 467
            |..::| |::|.|..:   ||    ..|..|...:|.    .||..|||||            |.
Human   103 VQQLHP-ALIQRPFGI---PAHYVYPQAFVQPGVVIP----HVQPTAAAAS------------TT 147

  Fly   468 PQTALHSVRYAPYSIPASAATANAALMQAHQAQSVAAAAHHHQQQQQQQHHHQQQTHNAHVAAAQ 532
            |........||.||..|:||.|.||..|...|.|.|||.:
Human   148 PYIDYTGAAYAQYSAAAAAAAAAAAYDQYPYAASPAAAGY------------------------- 187

  Fly   533 QQQQSHHNAVSNPASQAHSAAAAAALAANAANGAGAAGAHSLAAAAQQAGLMAGNPLNAAAAAAA 597
                                        ..|.|.|.|....:.|||         |..|||||||
Human   188 ----------------------------VTAGGYGYAVQQPITAAA---------PGTAAAAAAA 215

  Fly   598 AAANPAAAYSNY 609
            |||  |||:..|
Human   216 AAA--AAAFGQY 225

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.