DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment msi and HNRNPA3

DIOPT Version :9

Sequence 1:NP_001247303.1 Gene:msi / 43087 FlyBaseID:FBgn0011666 Length:634 Species:Drosophila melanogaster
Sequence 2:NP_001317178.1 Gene:HNRNPA3 / 220988 HGNCID:24941 Length:378 Species:Homo sapiens


Alignment Length:203 Identity:77/203 - (37%)
Similarity:118/203 - (58%) Gaps:13/203 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   186 GRSTPSLS------GGSGSDPAP----GKLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVT 240
            ||..|...      |..|.||..    .|||:||||::|:.|.|:|:|..:||:||.::|:||.|
Human     8 GRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQT 72

  Fly   241 QRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPKN---RPRQANKTKKIFVGGVSQDT 302
            :|||||||:|:.....|:..:....|.:||:.::||.|..:.   :|......|||||||:.:||
Human    73 KRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDT 137

  Fly   303 SAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVCEIHFHTIKNKKVECKKAQ 367
            ....::.||.::|.:|...::.|:|:.:.|||.||||::.|.||::....:|||.....|.|||.
Human   138 EEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKAL 202

  Fly   368 PKEAVTPA 375
            .|:.:..|
Human   203 SKQEMQSA 210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
msiNP_001247303.1 RRM1_hnRNPA_hnRNPD_like 205..276 CDD:240771 31/70 (44%)
RRM2_MSI 292..365 CDD:240769 28/72 (39%)
HNRNPA3NP_001317178.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35 7/26 (27%)
RRM1_hnRNPA_like 36..113 CDD:409992 35/76 (46%)
RRM2_hnRNPA3 126..205 CDD:409996 32/78 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 204..225 2/7 (29%)
HnRNPA1 331..>347 CDD:402981
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 336..378
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.