Protein Alignment msi and Rbm4

DIOPT Version :10

• Sequence 1: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_033058.2
• Gene: Rbm4 / 19653
• MGIID: 1100865
• Length: 361
• Species: Mus musculus
• Alignment Length: 425
• Identity: 88/425 - (20%)
• Similarity: 156/425 - (36%)
• Gaps: 84/425 - (19%)

  Fly   204 KLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMKDPVTQRSRGFGFITFQEPCTVEKVLKVPIHTL 268
            |||:|.|..:.:..:::..|..:|.|.:..|:|:        :||:..::....|..    |..|
Mouse     3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDA----IRNL 55

  Fly   269 DGKKIDPKHATPKNRPRQANKTK---KIFVGGVSQDTSAEEVKAYFSQFGPVEETVMLMDQQTKR 330
            ...|:   |....|.....||:|   |:.||.:|...:.:|::|.|.::|||.|..::.|
Mouse    56 HHYKL---HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD----- 112

  Fly   331 HRGFGFVTFEN-EDVVDRVCEIHFHTIKNKKVECKKAQPKEAVTPAAQLLQKRIMLGTLGVQLPT 394
               :.||..|. ||.|:.:     ..:.|.:.:.|:               ..:.|.|  .:|.|
Mouse   113 ---YAFVHMERAEDAVEAI-----RGLDNTEFQGKR---------------MHVQLST--SRLRT 152

  Fly   395 APGQLIGARGAGVATMNPLAMLQNPTQLLQSPAAAAAAQQAALISQNPFQVQNAAAAASIANQAG 459
            |||                        :..........::.....:.|  :..:...|.:..|..
Mouse   153 APG------------------------MGDQSGCYRCGKEGHWSKECP--IDRSGRVADLTEQYN 191

  Fly   460 --FGKLLTTYPQTALHSVRYAPYSIPASAATANAALMQAHQAQSVAAA---AHHHQQQQQQQHHH 519
              :|.:.|.|..:...|:.|........|........::::|.:.|||   :::.:|...|....
Mouse   192 EQYGAVRTPYTMSYGDSLYYNNTYGALDAYYKRCRAARSYEAVAAAAASAYSNYAEQTLSQLPQV 256

  Fly   520 QQQTHNAHVAAAQQQQQSHHNAVSNPASQAHSAAAAAALAANAANGAGAAGAHSLAAAAQQAGLM 584
            |.....:|:.:......:.|..   |.|.| :||||||.|..||:.:......|....|....|.
Mouse   257 QNTAMASHLTSTSLDPYNRHLL---PPSGA-AAAAAAAAACTAASTSYYGRDRSPLRRATGPVLT 317

  Fly   585 AGNPLNAAAAAAAAAANPAAAYSNYALANVDMSSF 619
            .|........:..:.|:.||..|.|.:|..:...:
Mouse   318 VGEGYGYGHDSELSQASAAARNSLYDMARYEREQY 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	16/73 (22%)
		RRM2_MSI	292..365	CDD:240769	19/73 (26%)
Rbm4	NP_033058.2	RRM1_RBM4	2..68	CDD:410018	18/79 (23%)
		RRM2_RBM4	78..144	CDD:410019	20/93 (22%)
		PTZ00368	<145..>181	CDD:173561	8/63 (13%)
		ZnF_C2HC	161..176	CDD:197667	0/14 (0%)
		Interaction with TNPO3. /evidence=ECO:0000250	196..361		36/161 (22%)